What are the signs and symptoms of pemphigus vulgaris in the oral cavity?

Updated: Jun 14, 2018
  • Author: Bassam Zeina, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Mucous membranes of the oral cavity are involved in almost all patients with pemphigus vulgaris.

Patients may have ill-defined, irregularly shaped, gingival, buccal, or palatine erosions, which are painful and slow to heal.

Intact bullae are rare in the mouth.

Erosions may be seen on any part of the oral cavity, and they may spread to involve the larynx, with subsequent hoarseness.

In juvenile pemphigus vulgaris, stomatitis is the presenting complaint in more than 50% of cases.

Other mucosal surfaces may be involved, including the conjunctiva, [2] esophagus (causes odynophagia and/or dysphagia), [3] labia, vagina, cervix, vulva, [4] penis, urethra, nasal mucosa, and anus.

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