What is the role of other therapies in the pathogenesis of bullous pemphigoid (BP)?

Updated: Oct 14, 2020
  • Author: Lawrence S Chan, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

A 2009 report of bullous pemphigoid developed after adalimumab treatment for psoriasis raises some question about whether biologics can play a role in inducing the disease or it may just suggest the association of bullous pemphigoid with psoriasis. [35]

Bullous pemphigoid has been associated with PD-1 inhibitors used as targeted therapy for malignancy. Some patients developed both pemphigoid and keratoacanthomas. [36, 37, 38]

Dipeptidyl peptidase 4 (DPP-4) inhibitors are associated with a risk of developing bullous pemphigoid. [39, 40, 41, 42]


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