What is included in the medical care of seborrheic keratosis?

Updated: Oct 14, 2020
  • Author: Arthur K Balin, MD, PhD, FACP; Chief Editor: William D James, MD  more...
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Answer

Ammonium lactate and alpha hydroxy acids have been reported to reduce the height of seborrheic keratoses. [32, 33] Superficial lesions can be treated by carefully applying pure trichloroacetic acid and repeating if the full thickness is not removed on the first treatment.

Topical treatment with tazarotene cream 0.1% applied twice daily for 16 weeks caused clinical improvement in seborrheic keratoses in 7 of 15 patients. [34]

In 2017, the US Food and Drug Administration (FDA) approved a concentrated hydrogen peroxide 40% solution (Eskata) for adults with raised seborrheic keratosis. The solution is available within an applicator pen and is administered in a medical office setting by a healthcare professional. [35]

A drug that inhibits the activity of Akt kinase is currently under development and may cause seborrheic keratoses to self-destruct. [15]


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