What is the role of topical 5-fluorouracil in the treatment of porokeratosis?

Updated: Oct 09, 2020
  • Author: Amarateedha Prak LeCourt, MD; Chief Editor: William D James, MD  more...
  • Print
Answer

Topical 5-fluorouracil can induce remission in all forms of porokeratosis. [72, 73] Treatment must be continued until a brisk inflammatory reaction is obtained. Enhancement of penetration, which heightens the response, may be achieved by occlusion or the addition of topical tretinoin, tazarotene, or salicylic acid. [74] Recurrences may be seen.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!