What are "B" findings indicative of a high systemic mastocytosis burden in patients?

Updated: Jun 07, 2018
  • Author: Jacquiline Habashy, DO, MSc; Chief Editor: Dirk M Elston, MD  more...
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Answer

Consultation with a hematologist may be necessary for a bone marrow biopsy and staging. The WHO classification of systemic mastocytosis mandates a number of staging investigations to define the exact subtype of disease. Identification of "B" findings alone, such as the following, is indicative of a high systemic mastocytosis burden:

  • Greater than 30% bone marrow mastocytosis burden

  • Serum tryptase level greater than 200 ng/mL


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