What are the treatment options for vascular collapse in patients with mastocytosis?

Updated: Jun 07, 2018
  • Author: Jacquiline Habashy, DO, MSc; Chief Editor: Dirk M Elston, MD  more...
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Answer

Medical alert bracelets should be made available, and an epinephrine self-injector demonstration should be performed and self-injector prescribed for patients with systemic mastocytosis or patients with episodes of vascular collapse. Patients with recurrent episodes of vascular collapse may be prophylactically placed on H1 and H2 antihistamines to lessen the severity of attacks. Episodes of vascular collapse may be spontaneous but have also occurred after stings from insects or after administration of iodinated contrast media for imaging studies. Premedication with antihistamines and corticosteroids is recommended before such procedures in patients at risk.


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