What is the role of urinary N-methylhistamine (NMH) and N-methylimidazoleacetic acid levels in the diagnosis of mastocytosis?

Updated: Jun 07, 2018
  • Author: Jacquiline Habashy, DO, MSc; Chief Editor: Dirk M Elston, MD  more...
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Answer

Urinary NMH and N-methylimidazoleacetic acid levels [32, 33]  may be more specific and sensitive than urinary histamine levels. NMH levels correlate directly with the extent of skin lesions. NMH levels decrease with age; therefore, consider the patient's age when interpreting results.


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