Which medications in the drug class Calcium Channel Blockers are used in the treatment of Keloid and Hypertrophic Scar?

Updated: Jun 12, 2018
  • Author: Brian Berman, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Calcium Channel Blockers

Treatment of keloids and hypertrophic scars with verapamil has shown a reduction in vascularity, pliability, height, and width of the lesions.

Verapamil (Isoptin, Calan, Verelan PM)

Verapamil blocks the synthesis and secretion of extracellular matrix molecules and increases fibrinase. It is not approved by the FDA for use in hypertrophic scars and keloids.


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