What is the role of direct antigen detection in the diagnosis of scarlet fever?

Updated: Jun 21, 2019
  • Author: Bahman Sotoodian, MD; Chief Editor: William D James, MD  more...
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Answer

Direct antigen detection kits (ie, rapid antigen tests [RATs], strep screens) have been proposed to allow immediate diagnosis and prompt administration of antibiotics. Kits are latex agglutination or a costlier enzyme-linked immunosorbent assay (ELISA). Several studies of RAT kits report results of 95% specificity but only 70-90% sensitivity. Operator technique can also significantly influence the results of the test. [24]


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