How is common variable immunodeficiency (CVID) treated during pregnancy?

Updated: Feb 23, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Answer

In pregnant patients with CVID and lung disease, the pulmonary deficit is often exacerbated in the third trimester. If the mother receives adequate IVIG replacement therapy during pregnancy, her neonate (with CVID) has IgG levels in the reference range because the antibody is actively transported across the placenta.


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