What are the approach considerations in the treatment of chronic urticaria?

Updated: Jul 31, 2018
  • Author: Marla N Diakow, MD; Chief Editor: William D James, MD  more...
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Nonsedating anti-H1 antihistamines remain the mainstay of treatment for chronic urticaria. If these agents are ineffective, higher dosages may be tried (up to four times the standard recommended dosage), or other agents may be substituted (see below).

Elimination of suspected triggers should be advocated. Avoidance of mental stress, [32] overtiredness, alcohol, nonsteroidal anti-inflammatory drugs (NSAIDs), and tight-fitting garments is recommended. Psychological stress can trigger or increase itching. [32] Nocturnal pruritus may be reduced by lukewarm bathing and keeping the ambient temperature of the bedroom cool. Application of lotions with menthol and phenol provide prompt relief of pruritus for some patients.

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