What is the prognosis of chronic urticaria?

Updated: Jul 31, 2018
  • Author: Marla N Diakow, MD; Chief Editor: William D James, MD  more...
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The primary manifestations of urticaria are rash and pruritus. The course of the disease is unpredictable, and it may last months to years. About 50% of patients experience remission within 1 year. [26] Only rarely does permanent hyperpigmentation or hypopigmentation occur. The only long-term consequences of chronic urticaria are anxiety and depression.

The prognosis in chronic urticaria depends on the comorbid disease causing the urticaria and the patient’s response to therapy. Several diseases associated with chronic urticaria can be associated with significant morbidity and mortality (eg, malignancies, systemic lupus erythematosus). Chronic urticaria can affect the patient’s quality of life, owing to the associated pruritus and loss of sleep. It can lead to anxiety and depression, with rare reports of suicide.

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