Which medications in the drug class Corticosteroids are used in the treatment of Id Reaction (Autoeczematization)?

Updated: Oct 16, 2020
  • Author: Matthew P Evans, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Corticosteroids

Corticosteroids help lesion resolution and provide symptomatic relief of pruritus. The strength and administration of a topical corticosteroid should be chosen based on the extent, location, and morphology of the eruption. Systemic corticosteroids may be used for severe or refractory eruptions.

Amcinonide (Cyclocort)

Amcinonide suppresses mitotic activity and causes vasoconstriction. It stimulates the synthesis of enzymes needed to decrease inflammation.

Fluocinonide (Fluonex, Lidex)

Fluocinonide is a high-potency steroid that inhibits cell proliferation. It is immunosuppressive, antiproliferative, and anti-inflammatory. It also has antipruritic and vasoconstrictive properties.

Prednisone (Orasone, Sterapred, Deltasone)

Prednisone is a commonly used oral agent. It is indicated for severe, prolonged, or anaphylactic reactions. It decreases late immune-mediated complications. Prednisone must be metabolized to the active metabolite prednisolone for effect. Conversion may be impaired in liver disease.

Methylprednisolone (Depo-Medrol, Medrol, Adlone, Solu-Medrol)

Methylprednisolone may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. It is indicated for severe, prolonged, or anaphylactic reactions. It decreases late immune-mediated complications.


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