Which histologic findings indicate TEN in drug eruptions?

Updated: Feb 15, 2019
  • Author: Jonathan E Blume, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Histopathology of TEN shows subepidermal split, full-thickness epidermal necrosis and a sparse perivascular lymphocytic infiltrate (see the image below).

Confluent necrosis of the epidermis in toxic epide Confluent necrosis of the epidermis in toxic epidermal necrolysis.

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