What should be included in the medication history of suspected drug eruptions?

Updated: Oct 14, 2020
  • Author: Jonathan E Blume, MD; Chief Editor: Dirk M Elston, MD  more...
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Note and detail the following:

  • All prescription and over-the-counter drugs, including topical agents, vitamins, and herbal and homeopathic remedies

  • The interval between the introduction of a drug and onset of the eruption

  • Route, dose, duration, and frequency of drug administration

  • Use of parenterally administered drugs, which are more likely than oral agents to cause anaphylaxis

  • Use of topically applied drugs, which are more likely than other drugs to induce delayed-type hypersensitivity reactions

  • Use of multiple courses of therapy and prolonged administration of a drug, which can cause allergic sensitization

  • Any improvement after drug withdrawal and any reaction with readministration

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