Which medications in the drug class Topical Phosphodiesterase-4 (PDE-4) Inhibitors are used in the treatment of Atopic Dermatitis?

Updated: Aug 02, 2019
  • Author: Brian S Kim, MD, MTR, FAAD; Chief Editor: William D James, MD  more...
  • Print
Answer

Topical Phosphodiesterase-4 (PDE-4) Inhibitors

A topical PDE-4 inhibitor is a nonsteroidal option for atopic dermatitis treatment.

Crisaborole topical (Eucrisa)

PDE-4 inhibitors allow for cyclic adenosine monophosphate (cAMP) to remain intact in order to decrease the proinflammatory response (eg, cytokine release) associated with atopic dermatitis. Crisaborole is indicated for mild-to-moderate atopic dermatitis in adults and children aged 2 years or older.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!