Which treatments for atopic dermatitis (eczema) have been shown to be effective?

Updated: Jun 03, 2020
  • Author: Brian S Kim, MD, MTR, FAAD; Chief Editor: William D James, MD  more...
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In patients with severe disease, and particularly in adults, phototherapy, methotrexate (MTX), [65, 66] azathioprine, cyclosporine, and mycophenolate mofetil [4] have been used with success.

Both hydroxyzine and diphenhydramine hydrochloride provide a certain degree of relief from itching but are not effective without other treatments.

Oil of evening primrose was believed to be effective, but in a randomized controlled study, it showed no benefit in children and little improvement in adults.

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