What is the natural course of atopic dermatitis (eczema)?

Updated: Jun 03, 2020
  • Author: Brian S Kim, MD, MTR, FAAD; Chief Editor: William D James, MD  more...
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Data from a study by Garmhausen et al indicate that the natural course of the disease can be divided into subgroups with different clinical features. [42] The most frequent course type (31.1% of the sample) was characterized by an early disease onset (before age 2 years) and a chronic persisting course through adulthood.

Of the 607 patients in the study, 85.7% were categorized into 5 main different course types. [42] The greatest differences in the number of sensitizations, total immunoglobulin E serum levels, and predilection of skin lesions were seen between subjects with early-onset disease and a chronic persisting course until adulthood and those with late-onset AD developing after age 20 years.

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