Which topical medications are typically used in the treatment of atopic dermatitis (eczema)?

Updated: Apr 26, 2021
  • Author: Brian S Kim, MD, MTR, FAAD; Chief Editor: William D James, MD  more...
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Agents typically used to treat AD include the following:

  • Moisturizers: Petrolatum, Aquaphor, or newer agents such as Atopiclair and Mimyx

  • Topical steroids (current mainstay of treatment; commonly used in conjunction with moisturizers): Hydrocortisone, triamcinolone, or betamethasone; ointment bases are generally preferred, particularly in dry environments

  • Broad immunomodulators: Tacrolimus and pimecrolimus (calcineurin inhibitors; generally considered second-line therapy)

  • Targeted biologic therapies: Dupilumab (anti-IL-4Ra monoclonal antibody)

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