What are the aspects of a comprehensive physical exam for enuresis?

1. Robson WL. Clinical practice. Evaluation and management of enuresis. N Engl J Med. 2009 Apr 2. 360 (14):1429-36. [Medline].

2. Robson WL, Leung AK, Van Howe R. Primary and secondary nocturnal enuresis: similarities in presentation. Pediatrics. 2005 Apr. 115 (4):956-9. [Medline].

3. Moffatt ME. Nocturnal enuresis: psychologic implications of treatment and nontreatment. J Pediatr. 1989 Apr. 114 (4 Pt 2):697-704. [Medline].

4. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Arlington, VA: American Psychiatric Association; 2013. 355-7.

5. von Gontard A, Eiberg H, Hollmann E, Rittig S, Lehmkuhl G. Molecular genetics of nocturnal enuresis: linkage to a locus on chromosome 22. Scand J Urol Nephrol Suppl. 1999. 202:76-80. [Medline].

6. Arnell H, Hjälmås K, Jägervall M, Läckgren G, Stenberg A, Bengtsson B, et al. The genetics of primary nocturnal enuresis: inheritance and suggestion of a second major gene on chromosome 12q. J Med Genet. 1997 May. 34 (5):360-5. [Medline]. [Full Text].

7. Nørgaard JP, Pedersen EB, Djurhuus JC. Diurnal anti-diuretic-hormone levels in enuretics. J Urol. 1985 Nov. 134 (5):1029-31. [Medline].

8. Eggert P, Kühn B. Antidiuretic hormone regulation in patients with primary nocturnal enuresis. Arch Dis Child. 1995 Dec. 73 (6):508-11. [Medline].

9. Rittig S, Knudsen UB, Nørgaard JP, Gregersen H, Pedersen EB, Djurhuus JC. Diurnal variation of plasma atrial natriuretic peptide in normals and patients with enuresis nocturna. Scand J Clin Lab Invest. 1991 Apr. 51 (2):209-17. [Medline].

10. Mattsson S, Lindström S. Diuresis and voiding pattern in healthy schoolchildren. Br J Urol. 1995 Dec. 76 (6):783-9. [Medline].

11. Bloom DA, Seeley WW, Ritchey ML, McGuire EJ. Toilet habits and continence in children: an opportunity sampling in search of normal parameters. J Urol. 1993 May. 149 (5):1087-90. [Medline].

12. von Gontard A, Mauer-Mucke K, Plück J, Berner W, Lehmkuhl G. Clinical behavioral problems in day- and night-wetting children. Pediatr Nephrol. 1999 Oct. 13 (8):662-7. [Medline].

13. Baek M, Park K, Lee HE, Kang JH, Suh HJ, Kim JH, et al. A nationwide epidemiological study of nocturnal enuresis in Korean adolescents and adults: population based cross sectional study. J Korean Med Sci. 2013 Jul. 28 (7):1065-70. [Medline]. [Full Text].

14. Fergusson DM, Horwood LJ, Shannon FT. Secondary enuresis in a birth cohort of New Zealand children. Paediatr Perinat Epidemiol. 1990 Jan. 4 (1):53-63. [Medline].

15. Butler RJ. Impact of nocturnal enuresis on children and young people. Scand J Urol Nephrol. 2001 Jun. 35 (3):169-76. [Medline].

16. Glazener CM, Evans JH, Peto RE. Alarm interventions for nocturnal enuresis in children. Cochrane Database Syst Rev. 2005 Apr 18. CD002911. [Medline].

17. Glazener CM, Evans JH. Desmopressin for nocturnal enuresis in children. Cochrane Database Syst Rev. 2002. CD002112. [Medline].

18. Caldwell PH, Sureshkumar P, Wong WC. Tricyclic and related drugs for nocturnal enuresis in children. Cochrane Database Syst Rev. 2016 Jan 20. CD002117. [Medline].

19. Rittig N, Hagstroem S, Mahler B, Kamperis K, Siggaard C, Mikkelsen MM, et al. Outcome of a standardized approach to childhood urinary symptoms-long-term follow-up of 720 patients. Neurourol Urodyn. 2014 Jun. 33 (5):475-81. [Medline].

20. [Guideline] Vande Walle J, Rittig S, Bauer S, Eggert P, Marschall-Kehrel D, Tekgul S, et al. Practical consensus guidelines for the management of enuresis. Eur J Pediatr. 2012 Jun. 171 (6):971-83. [Medline]. [Full Text].

21. Robson WL, Nørgaard JP, Leung AK. Hyponatremia in patients with nocturnal enuresis treated with DDAVP. Eur J Pediatr. 1996 Nov. 155 (11):959-62. [Medline].

Wm Lane M Robson, MA, MD, FRCP, FRCP(Glasg) Medical Director, The Children's Clinic

Wm Lane M Robson, MA, MD, FRCP, FRCP(Glasg) is a member of the following medical societies: Royal College of Physicians and Surgeons of Canada, Royal College of Physicians and Surgeons of Glasgow, Royal Society for Public Health

Disclosure: Nothing to disclose.

Marc Cendron, MD Associate Professor of Surgery, Harvard School of Medicine; Consulting Staff, Department of Urological Surgery, Children's Hospital Boston

Marc Cendron, MD is a member of the following medical societies: American Academy of Pediatrics, American Urological Association, New Hampshire Medical Society, Society for Pediatric Urology, Society for Fetal Urology, Johns Hopkins Medical and Surgical Association, European Society for Paediatric Urology

Disclosure: Nothing to disclose.

Harry P Koo, MD Chairman of Urology Division and Director of Pediatric Urology, Professor of Surgery, Virginia Commonwealth University School of Medicine, Medical College of Virginia; Director of Urology, Children's Hospital of Richmond

Harry P Koo, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, and American Urological Association

Disclosure: Nothing to disclose.

Howard M Snyder III, MD Professor, Department of Surgery, Division of Pediatric Urology, University of Pennsylvania School of Medicine and Children's Hospital of Philadelphia

Howard M Snyder III, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, American Medical Association, American Urological Association, and National Kidney Foundation

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.