Which medications in the drug class Tumor Necrosis Factor Inhibitor are used in the treatment of Vasculitis and Thrombophlebitis?

Updated: Dec 10, 2018
  • Author: Nadia Jennifer Chiara Luca, MD; Chief Editor: Lawrence K Jung, MD  more...
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Answer

Tumor Necrosis Factor Inhibitor

Blocks the process by which activated neutrophils adhere to endothelium and stimulate lysis of endothelial cells in the presence of TNF-alpha.

Infliximab (Remicade)

Chimeric IgG1k monoclonal antibody that neutralizes cytokine TNF-alpha and inhibits its binding to TNF-alpha receptor. Reduces infiltration of inflammatory cells and TNF-alpha production in inflamed areas.


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