What is the role of surgery in the treatment of vasculitis?

Updated: Dec 10, 2018
  • Author: Nadia Jennifer Chiara Luca, MD; Chief Editor: Lawrence K Jung, MD  more...
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With involvement of the aorta and renal arteries, angioplasty and stenting of stenotic vessels has been used to improve flow (eg, in Takayasu arteritis). A significant proportion of vessels may develop restenosis, but good response to repeat procedure is noted. [47] In addition, reconstructive surgery with graft implantation may be required. Note that vascular procedures must be done during periods of inactive disease.

Patients with Wegener granulomatosis may develop subglottic stenosis; these lesions can be amenable to endoscopic management with local corticosteroid injection and/or mitomycin-C application. [48] Note that in granulomatosis with polyangiitis (formerly Wegener granulomatosis), repeated procedures are often necessary, and some patients may require tracheostomy insertion.

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