Which general lab findings are characteristic of vasculitis?

Updated: Dec 10, 2018
  • Author: Nadia Jennifer Chiara Luca, MD; Chief Editor: Lawrence K Jung, MD  more...
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Answer

CBC count and differential may reveal normochromic, normocytic anemia; leukocytosis; thrombocytosis consistent with inflammatory process; and eosinophilia in Churg-Strauss syndrome.

Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) may be elevated, but these findings are not sensitive or specific.

C3 and C4 levels are usually elevated, except in hypocomplementemic urticarial vasculitis.

Albumin levels may be low due to chronic inflammation, third spacing, or vascular leakage.

von Willebrand factor antigen (factor VIII-related antigen) may be elevated.


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