What are the diagnostic criteria for enthesitis-related juvenile idiopathic arthritis (JIA)?

Updated: Jul 25, 2019
  • Author: David D Sherry, MD; Chief Editor: Lawrence K Jung, MD  more...
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Diagnostic criteria for enthesitis-related JIA are the presence of both arthritis and enthesitis, or the presence of arthritis or enthesitis along with any 2 of the following 5 manifestations [21] :

  • Sacroiliac tenderness and/or inflammatory lumbosacral pain

  • Positive human leukocyte antigen B27 (HLA-B27) test

  • Onset of arthritis in a male 6 years old or older

  • Acute symptomatic anterior uveitis

  • Presence in a first-degree relative of ankylosing spondylitis, enthesitis-related arthritis, inflammatory bowel disease with sacroiliitis, reactive arthritis, or acute anterior uveitis

Although enthesitis can be observed in persons with oligoarticular and polyarticular JIA, the eventual development of arthritis into a predominant enthesitis is more characteristic of spondyloarthropathy. The radiographic changes observed in adults (eg, sclerosis of the sacroiliac joints, bamboo spine) are rare in childhood and adolescence.

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