Which medications in the drug class Vitamins are used in the treatment of Cystic Fibrosis?

Updated: Jun 26, 2019
  • Author: Girish D Sharma, MD, FCCP, FAAP; Chief Editor: Kenan Haver, MD  more...
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Answer

Vitamins

Vitamins are organic substances required by the body in small amounts for various metabolic processes. They may be synthesized in small or insufficient amounts in the body or not synthesized at all, thus requiring supplementation. They are classified as fat or water soluble. Vitamins A, D, E, and K are fat soluble while biotin, folic acid, niacin, pantothenic acid, B vitamins (ie, B-1, B-2, B-6, B-12), and vitamin C are generally water soluble.

Vitamin deficiency may result from an inadequate diet, increased requirements (eg, pregnancy, lactation), or secondary to disease or drug use. Vitamins are clinically used for the prevention and treatment of specific vitamin deficiency states. Supplementation of fat-soluble vitamins is routine in cystic fibrosis because of chronic malabsorption.

Vitamin A (Aquasol A)

Vitamin A is a fat-soluble vitamin and is essential for antioxidant effects and as coenzymes for biological pathways, neurodevelopment, bone development, and coagulation. Typical multivitamin preparations formulated especially for patients with CF are referred to as ADEKs. Doses vary by patient age.

Vitamin D (1,25-Dihydroxycholecalciferol, Calciferol, Cholecalciferol)

Vitamin D is a fat-soluble vitamin and is essential for antioxidant effects and as coenzymes for biological pathways, neurodevelopment, bone development, and coagulation. Typical multivitamin preparations formulated especially for patients with CF are referred to as ADEKs. Doses vary by patient age.

Vitamin E (Alpha-tocopherol, Aquasol E, Tocopherol)

Vitamin E is a fat-soluble vitamin and is essential for antioxidant effects and as coenzymes for biological pathways, neurodevelopment, bone development, and coagulation. Typical multivitamin preparations formulated especially for patients with CF are referred to as ADEKs. Doses vary by patient age.

Vitamin K1 (phytonadione) (AquaMephyton, Mephyton)

Vitamin K is a fat-soluble vitamin and is essential for antioxidant effects and as coenzymes for biological pathways, neurodevelopment, bone development, and coagulation. Typical multivitamin preparations formulated especially for patients with CF are referred to as ADEKs. Doses vary by patient age.


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