(ISSN: 0009-2797, 1872-7786)
Chemico-biological interactions's Latest Table of Contents
2016 - 255
- Editorial: Promising approaches to identify DILI drugs.
- Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse.
- The cytochrome P450 inhibitor SKF-525A disrupts autophagy in primary rat hepatocytes.
- In��vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
- In��vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review.
- Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes.
- Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles.
- Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.
- Drugs of abuse and addiction: A slippery slope toward liver injury.
- Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development.
- Oxidative stress markers, secondary bile acids and sulfated bile acids classify the clinical liver injury type: Promising diagnostic biomarkers for cholestasis.