(ISSN: 1356-5524, 1473-6810)
Articles Available on Medscape
- New Reversal Agent for Factor Xa Inhibitors Shows Promise
- Clinicians Should Think Twice Before Prescribing DPP-4 Inhibitors for Diabetes
- Early Exposure to Dogs and Farm Animals Reduces Risk of Childhood Asthma
- Non-toxigenic Clostridium difficile to Prevent Recurrent C. difficile Infection
- Dextromethorphan and Quinidine Are Suitable for Off-Label Short-Term Treatment of Agitation in People With Alzheimer's Disease Following First-Line Non-Drug Approaches
Evidence-Based Medicine's Latest Table of Contents
2016 - 21 (3)
- Treatment for chronic Strongyloides stercoralis infection: moderate-to-low evidence shows that ivermectin is more effective and tolerable than albendazole and thiabendazole, respectively.
- Why doctors should convey the medical consensus on vaccine safety.
- No new evidence to support the routine use of steroids in the treatment of infectious mononucleosis.
- Response to commentary by D Roth.
- Clinical judgment is not pass�� when it comes to identifying patients with acute myocardial infarction.
- Fidgeting is associated with lower mortality risk.
- High-sensitivity troponin predicts coronary disease outcomes in type 2 diabetes but yields no benefit in selecting patients for revascularisation.
- Prophylactic tranexamic acid in addition to uterotonics may prevent blood loss for vaginal and caesarean deliveries.
- Preoperative treatment with ��-blockers is associated with elevated postoperative mortality and cardiac morbidity in patients with uncomplicated hypertension undergoing non-cardiac surgery.
- Antiretroviral pre-exposure prophylaxis for HIV prevention is highly effective in community settings.
- Many US adults with controlled type 2 diabetes receive frequent HbA1c testing and possible overtreatment.
- Influenza vaccination and egg allergy: another step forward.
- In hypertensive patients with elevated risk of cardiovascular disease, targeting systolic blood pressure to less than 120���mm���Hg significantly reduces the rate of fatal and non-fatal cardiovascular events as well as death from any cause.
- Adjunctive use of intrapartum foetal ST-segment analysis (STAN) confers no benefit over conventional foetal heart rate monitoring.
- Limited data suggest that otherwise healthy school-aged children with obstructive sleep disordered breathing have some benefit from adenotonsillectomy compared with non-surgical treatment.
- Higher coffee consumption is associated with lower risk of all-cause and cause-specific mortality in three large prospective cohorts.
- High prevalence of depression in medical residents: the sad reality of medical training.
- Antenatal dietary education and/or balanced nutritional supplementation benefits at-risk women and infants.
- Fetal-neonatal iron deficiency is associated with poorer auditory recognition memory at 2���months of age.
- In newborns, oral or rectal paracetamol fails to reduce procedural pain, whereas intravenous paracetamol reduces morphine requirements after major surgery.
- Both paroxetine and imipramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety.
- Insomnia is associated with risk of future cardiovascular events irrespective of comorbidities.
- Cardiac resynchronisation therapy with an implantable cardioverter defibrillator appears to be cost-effective in patients with mild heart failure.
- Appropriate design, methodological quality assessment, and clinically relevant outcomes are essential to determine the therapeutic role of epidural injections for low back pain and radiculopathy.
- Drug-eluting stents and drug-eluting balloons are the best strategies to treat coronary in-stent restenosis.
- The combination of maternal early pregnancy characteristics and current antenatal blood pressure measurement from 28���weeks' gestation improves the prediction of women at risk of developing pre-eclampsia.
- Revascularisation plus supervised exercise is superior to supervised exercise alone for the treatment of intermittent claudication.
- Pertussis has low prevalence in adults with acute cough and is difficult to distinguish clinically from other causes.
- Detemir is non-inferior to NPH insulin in women with pregestational type 2 diabetes and gestational diabetes mellitus.
- Filtered sunlight reduces serum bilirubin levels as effectively as conventional phototherapy in late preterm and term neonates with mild jaundice.
- Lumacaftor-ivacaftor (Orkambi) for cystic fibrosis: behind the 'breakthrough'.