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Dendritic Cells and Aging: Consequences for Autoimmunity
The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens.
February 05, 2012
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The Role of Human Defensins in Gastrointestinal Diseases
Deepen your understanding of how the human immune system protects organisms with layered defenses of increasing specificity using mechanical, chemical and biological barriers.
January 06, 2012
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Primary Treatment of Crohn's Disease
The rationale for using antibiotics as primary treatment of Crohn's disease is based on increasing evidence that gut bacteria are the root of the problem, but will they help or hinder -- in the long run?
December 08, 2011
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The Role of Mast Cells in Male Infertility
Learn more about the potential effects of treatment with mast cell blockers on impaired male fertility.
November 07, 2011
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Understanding the Link Between the IL-6 Cytokine Family and Pregnancy
Cytokines are involved in almost all processes during the menstrual cycle, the fertilization period and pregnancy, but can their role be exploited in order to treat reproductive pathologies?
October 06, 2011
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Relevance of Rituximab Therapy in Pemphigus Vulgaris
The monoclonal antibody rituxamab holds promise in the treatment of recalcitrant pemphigus vulgaris, showing a significantly better response than standard therapy in this study.
September 01, 2011
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Epigenetic Modifications: Novel Therapeutic Strategies for Systemic Sclerosis?
Epigenetic modifications may offer novel therapeutic strategies for the treatment of systemic sclerosis by reversing the aberrant production of extracellular matrix proteins.
August 10, 2011
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The Basophil Activation Test in the Diagnosis of Immediate Drug Hypersensitivity
Going to BAT provides the physician with an additional instrument to diagnose drug allergy and to tailor possible safe alternatives.
July 01, 2011
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The Risk of Tuberculosis in Patients Treated With TNF Antagonists
TNF antagonists have been successfully used for the treatment of chronic inflammatory disorders, but clinical trial data show that patients treated with these biologics have an increased risk of reactivating latent TB.
June 02, 2011
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Systemic Lupus Erythematosus and Cardiovascular Disease
Atherosclerotic plaque is largely driven by inflammation and an active immunological response. Learn more about targeting cardiovascular risk factors for patients with lupus.
April 28, 2011
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A Glass of Red Wine to Keep Vascular Disease at Bay, but What About Pemphigus Vulgaris?
Tannins are widely distributed in many foods and beverages and seem to have both beneficial and potentially harmful effects.
March 29, 2011
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Advances in Proteomic Techniques for Biomarker Discovery in COPD
The molecules identified as potential biomarkers of COPD may represent a preliminary step for better comprehension of the mechanisms involved in the onset/progression of the disease.
January 25, 2011
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Protection Against or Triggering of Type 1 Diabetes? Different Roles for Viral Infections
Authors disentangle parts of the complex interplay between viruses and the immune system.
January 10, 2011
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Current Understanding and Management of Giant Cell Arteritis and Polymyalgia Rheumatica
This article reviews recent guidelines on early diagnosis, investigations and management of these two diseases impacting the elderly.
November 28, 2010
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Recent Advances in the Treatment of Eosinophilic Esophagitis
Medical, nutritional, and mechanical treatments to relieve the symptoms of eosinophilic esophagitis are discussed.
November 15, 2010
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Innate Antimicrobial Immunity in Inflammatory Bowel Diseases
Recent advances support the evolving hypothesis that intestinal bacteria induce inflammation in genetically predisposed individuals.
October 29, 2010
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RAPID and FAST4WARD Trials: Certolizumab Pegol for Rheumatoid Arthritis
Rheumatoid arthritis treatment options are rapidly expanding and this article will bring you up-to-speed.
September 28, 2010
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Inflammatory Bowel Disease and Pregnancy: an Update
Pregnancy and IBD are not an ideal mix, but with the proper treatment the two conditions can be successfully managed.
August 06, 2010
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Current Status of Monoclonal Antibody Therapy for the Treatment of Inflammatory Bowel Disease
Both older and newer agents approved for the treatment of ulcerative colitis and Crohn’s disease are reviewed.
July 30, 2010
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Autism Spectrum Disorders and Allergy: Observation From a Pediatric Allergy/Immunology Clinic
Overlap between allergic diseases and autism spectrum disorders can lead to confusion regarding the origin of certain symptoms.
June 15, 2010
