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Composite Lymphocyte-rich Thymoma and Peripheral T-Cell Lymphoma Not Otherwise Specified
Review the diagnostic findings in this unique and complex case of a woman with composite thymoma and peripheral T-cell lymphoma not otherwise specified.
May 11, 2012
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Increased Need for Testing to Confirm Initial Weakly Reactive Results for Hepatitis B Virus Surface Antigen
Standard procedure for diagnosing HBV infection is to repeat test results in specimens with borderline levels of HBsAg. Can the gray zone within which a confirmatory test is needed be better defined?
May 04, 2012
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Results of a Quality Improvement Program for Sweat Testing to Diagnose Cystic Fibrosis
Obtaining an adequate volume of sweat from an infant to perform sweat testing for cystic fibrosis has remained a challenge. Can a quality improvement initiative increase efficiency?
April 27, 2012
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Evaluation of an Abbreviated Centrifugation Protocol for Chemistry Testing
In most situations, time is of the essence when delivering lab results. Would a shorter centrifugation time adversely affect the accuracy or precision of most assays?
April 06, 2012
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Comparison of Two Enzyme Immunoassays for Detecting Mycoplasma pneumoniae
To initiate appropriate antibiotic therapy for pneumonia, the etiological agent must be identified. This study compared serologic tests commonly used for the diagnosis of M. pneumoniae infection.
March 30, 2012
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Repetitive-sequence-based Genotyping and Clonal Relationship Analysis of Acinetobacter baumannii in Nosocomial Infections
This review demonstrates the use of the rep-PCR-based DiversiLab Microbial Typing System in determining the epidemiological status of nosocomial A. baumannii infections.
March 23, 2012
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Pre-analytical Variables in Coagulation Testing Associated With Diagnostic Errors in Hemostasis
Review pre-analytical variables affecting various coagulation tests and learn how errors can be avoided in this comprehensive overview.
March 04, 2012
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Multiple Positive Sweat Chloride Tests in an Infant Asymptomatic for Cystic Fibrosis
This 1-month old infant has several laboratory findings associated with cystic fibrosis, including multiple positive sweat chloride tests; yet presents with no symptoms. Does he have CF?
February 26, 2012
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A Review of Medical Errors in Laboratory Diagnostics and Where We Are Today
While many areas of health care are still struggling with the issue of patient safety, the area of laboratory diagnostics has made significant progress. But there is still need for improvement.
February 19, 2012
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The Laboratory Diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH)
This review presents a history of diagnostic laboratory tests for paroxysmal nocturnal hemoglobinuria, a rare acquired stem cell disorder.
January 12, 2012
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Blood Sample Processing
This report from a panel of leading clinical pathologists focuses on recent key issues surrounding blood sample processing, including a push for smaller sample size, automated systems, and more.
January 05, 2012
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33-year-old Liver Transplant Recipient Returns From Hunting Trip in Sudan With Intermittent Fevers and Gross Hematuria
Given this patient's symptoms and history of recent African travel, there were several possible viruses which could be responsible for his hemorrhagic fever. What did lab tests reveal?
December 29, 2011
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In Silico Evaluation and Testing of Fluorescence In Situ Hybridization 16S rRNA Probes for Staphylococcus aureus
This review evaluates six different online computational tools for assessment of candidate FISH probes for S. aureus. How accurate are they?
December 22, 2011
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Setting Up a Standardized Peripheral Blood Mononuclear Cells Processing Laboratory to Support Multi-center HIV/AIDS Vaccine and Intervention Trials
This article describes the challenges of creating a sustainable cell processing lab for HIV and AIDS-related clinical trials at a rural field site in Africa.
December 15, 2011
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Falsely Elevated Parathyroid Hormone-related Protein (PTH-RP) in a Patient With Hypercalcemia and Renal Failure
Hypercalcemia is often associated with cancer, but this patient with renal failure and hypercalcemia showed no obvious malignancy. What was the cause of his elevated PTH-RP?
December 09, 2011
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Delayed Hemolytic Transfusion Reaction Without Detectable Autoantibodies or Alloantibodies
In this unusual case, a sickle-cell patient experienced a delayed hemolytic transfusion reaction without the usually observed autoantibodies or alloantibodies. What factors may have played a role?
November 21, 2011
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(1-3)-Beta-D-Glucan Assay
Invasive fungal infections are associated with significantly high morbidity and mortality. This review highlights a new assay that can be used to aid in the diagnosis of these serious infections.
November 14, 2011
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New Contrast Stain for the Rapid Diagnosis of Dermatophytosis and Pityriasis Versicolor
The authors describe a rapid, reliable, and easy to interpret diagnostic method for dermatophyte infection and pityriasis versicolor utilizing a new staining agent.
November 08, 2011
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Hematologic Markers of Influenza A H1N1 for Early Laboratory Diagnosis and Treatment Assessment
Early laboratory diagnosis of influenza A H1N1 infection would be beneficial to improving the survival rate. Is there a reliable hematologic marker that can be considered diagnostic of this disease?
October 27, 2011
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Digital Pathology: A Regulatory Overview
With digital pathology now entering clinical laboratories, it is crucial for laboratory professionals to understand the regulatory requirements and how to best implement them.
October 13, 2011
