Drug Insight: Gastrointestinal and Hepatic Adverse Effects of Molecular-Targeted Agents in Cancer Therapy CME

Copyright © 2008 Medscape.


CME Information

Target Audience

This activity is intended for primary care physicians, oncologists, gastroenterologists, and other physicians who care for patients receiving molecular targeted therapy.

Goal

The goal of this activity is to review the adverse effects of molecular targeted therapy on the gastrointestinal system.

Learning Objectives for This Educational Activity

  1. Describe the clinical presentation of diarrhea caused by molecular targeted therapy
  2. Specify a recommended treatment for diarrhea caused by molecular targeted therapy
  3. Describe hepatitis associated with molecular targeted therapy
  4. Identify the pathophysiology and clinical management of elevated pancreatic enzymes associated with molecular targeted therapy

Credits Available

Physicians - maximum of 1.0 AMA PRA Category 1 Credit(s) for physicians

All other healthcare professionals completing continuing education credit for this activity will be issued a certificate of participation.

Physicians should only claim credit commensurate with the extent of their participation in the activity.

Accreditation Statements

Learning Objectives

Upon completion of this activity, participants will be able to:

  1. Describe the clinical presentation of diarrhea caused by molecular targeted therapy
  2. Specify a recommended treatment for diarrhea caused by molecular targeted therapy
  3. Describe hepatitis associated with molecular targeted therapy
  4. Identify the pathophysiology and clinical management of elevated pancreatic enzymes associated with molecular targeted therapy
Authors and Disclosures

Yohann Loriot, MD
Disclosure: Yohann Loriot, MD, has disclosed no relevant financial relationships.


Gabriel Perlemuter, MD
Disclosure: Gabriel Perlemuter, MD, has disclosed no relevant financial relationships.


David Malka, MD, PhD
Disclosure: David Malka, MD, PhD, has declared that he is on the speakers bureau for Merck, Pfizer, Roche, sanofi-aventis and Serano, and receives grant or research support from Merck, Roche, sanofi-aventis and Serano.


Frédérique Penault-Lorca, MD
Disclosure: Frédérique Penault-Lorca, MD, has disclosed no relevant financial relationships.


Valérie Boige, MD
Disclosure: Valérie Boige, MD, has disclosed no relevant financial relationships.


Eric Deutsch, MD, PhD
Disclosure: Eric Deutsch, MD, PhD, has disclosed no relevant financial relationships.


Christophe Massard, MD, MSc
Disclosure: Christophe Massard, MD, MSc, has disclosed no relevant financial relationships.


Jean Pierre Armand, MD
Disclosure: Jean Pierre Armand, MD, has disclosed no relevant financial relationships.


Jean-Charles Soria, MD, PhD
Disclosure: Jean-Charles Soria, MD, PhD, has declared a consultant relationship with Roche, sanofi-aventis, and Wyeth. Dr. Soria has also declared that he receives grant or research support from Eli Lilly.


Charles P. Vega, MD
Disclosure: Charles P. Vega, MD, has disclosed that he has served as an advisor or consultant to Novartis, Inc.


Lisa Hutchinson
Disclosure: Lisa Hutchinson has disclosed no relevant financial relationships.


For Physicians

Medscape

Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Medscape, LLC designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.


For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity: CME@medscape.net. For technical assistance, contact CME@webmd.net.

Release Date: March 18, 2008Valid for credit through March 18, 2009

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. Medscape encourages you to complete the Activity Evaluation to provide feedback for future programming.
You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates by accessing "Edit Your Profile" at the top of your Medscape homepage.

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