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Medscape Conference Coverage, based on selected sessions at the:
XIV International Symposium on Atherosclerosis (ISA 2006)
June 18 - 22, 2006, Rome, Italy

This activity is not sanctioned by, nor a part of, XIV International Symposium on Atherosclerosis.


Topic Overviews
The apo B/A-I Ratio -- A Stronger Predictor of Cardiovascular Events Than LDL, HDL, or Total Cholesterol, Triglycerides, or Lipid Ratios
Assessment of LDL-cholesterol levels to predict future CVD risk has barely become standard of care, and now analysis of data from 3 large trials shows that the apo B/A-I ratio is conclusively superior.
Statin Therapy With or Without Ezetimibe in Patients at High Risk for Cardiovascular Disease
Two recent clinical trials, including EXPLORER, examined whether the best way to achieve the latest, ever lower LDL-cholesterol targets should be with the highest dose of a statin, or with combination therapy.
Coadministration of Ezetimibe-Simvastatin and Fenofibrate in Patients With Mixed Hyperlipidemia
For those difficult patients with the constellation of mixed hyperlipidemia, is a cocktail of drugs the most successful approach?
COMPELL: Comparative Effects on Lipid Levels of Niaspan and Statins vs Other Lipid Therapies
For dyslipidemic patients who need substantial triglyceride lowering and HDL increases, in addition to LDL lowering, is the best approach more statin or added niacin?
Aggressive Risk-Factor Modification in Patients With Subclinical Atherosclerosis Reduces Plaque Burden and Regresses Carotid Artery Wall Thickness
Recent clinical trials have said that lowering LDL cholesterol to < 75 mg/dL stops progression and may even regress atherosclerosis, but an observational study found that these LDL levels may not be necessary.
OCEAN: Omacor Carotid Endarterectomy Intervention Trial
There have been several reports of benefit for omega-3 fatty acids against atherosclerotic disease, but until the OCEAN trial, the physiologic mechanisms of the benefits were unclear.

 
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