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The GI Cancer Challenge: Establishing Treatment Strategies Within the Evolving Paradigm CME
Co-Chairs: Jaffer A. Ajani, MD; Mace L. Rothenberg, MD; Faculty: David Cunningham, MD, FRCP; David H. Ilson, MD, PhD; George D. Demetri, MD; Jean-Yves Douillard, MD, PhD; Heinz-Josef Lenz, MD, FACP
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Release Date: July 20, 2004Valid for credit through July 20, 2005

This activity has expired.
CME in this activity indicates that it was developed according to ACCME guidelines and was certified for credit by one or more accredited CME or CE providers. Medscape cannot attest to the timeliness of expired CME activities.


This CME activity is based on transcripts and slides of presentations as delivered by the faculty at the "The GI Cancer Challenge: Establishing Treatment Strategies Within the Evolving Paradigm" symposium held at the Sheraton New Orleans Hotel in New Orleans, Louisiana on June 4, 2004.

Contents of This CME Activity
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  1. Welcome Remarks
    by Mace L. Rothenberg, MD
    Overview and Objectives

  2. A Global Perspective on Recent Advances, Challenges, and Opportunities in the Treatment of GI Cancers
    by David H. Ilson, MD, PhD
    Gastrointestinal Cancers: Incidence and Prevention
    Colorectal Cancer: Progress in Survival and Response to Therapy
    Gastric/Esophageal Cancer: Adjuvant Therapies
    Gastric/Esophageal Cancer: Combining Modalities, Combining Drugs
    Tailoring Therapy to the Patient and Moving Forward

  3. Predicting Cancer Risk and Clinical Outcomes: The Impact of Pharmacogenomics in Colorectal Cancer
    by Heinz-Josef Lenz, MD
    Markers in Colorectal Cancer
    Genetic Polymorphisms
    TS Polymorphism and Gene Expression
    TS Polymorphism and Cancer Treatments
    Genetic Polymorphisms: Types, Frequency, and Patient Survival
    Genetic Polymorphisms and Patient Response to Chemotherapy
    The Future

  4. Therapeutic Advances and Enhancing Outcomes for Gastroesophageal Cancers
    by David Cunningham, MD
    The Case for Preoperative Chemotherapy in Esophageal Cancer
    Gastric Cancer: Postoperative Chemoradiation
    Perioperative Chemotherapy
    Perioperative Chemotherapy vs Postoperative Chemoradiotherapy
    Metabolic Response
    The REAL 2 Study
    The Taxanes
    Irinotecan in Gastroesophageal Cancer: 2 Studies
    An Irinotecan/Docetaxel Study
    The Role of Epidermal Growth Factor Receptor

  5. The GIST Revolution: Advancing Targeted Therapies and Outcomes
    by George D. Demetri, MD
    Molecular Switches
    Mutation and Targeted Therapy
    GIST: Response to Imatinib and Functional Imaging
    Survival With Imatinib
    Molecular Anatomy and Disease Progression
    A New Generation of Drugs
    Primary Resistance to Imatinib: A Case
    Mechanisms Will Link Diseases

  6. The New Generation of Colorectal Cancer Therapy: Extending Survival and the Continuum of Care
    by J. Y. Douillard, MD, PhD
    Efficacy of Current Therapeutic Drug Combinations
    Scheduling Combination Therapy
    The GERCOR Trial: Design and Results
    GERCOR: Toxicity, Safety, Personal Conclusions
    Infusional 5-FU or Oral Fluoropyrimidine
    Adding Bevacizumab
    The Future

  7. Closing Remarks
    by Jaffer A. Ajani, MD

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Copyright © 2004 the Academy for Healthcare Education.



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