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Medscape Conference Coverage, based on selected sessions at the:
Second International AIDS Society Conference on HIV Pathogenesis and Treatment
July 13 - 16, 2003, Paris, France

Medscape is the official provider of online conference coverage and continuing medical education activities based on the
Second IAS Conference on HIV Pathogenesis and Treatment.


Also On This Page:Conference NewsExpert Commentary and Interviews
International PerspectivesDownloadsSpecial PresentationsHIV Science

Topic Overviews
Antiretroviral Therapy and Therapeutic Strategies CME
Physicians - up to 1.5 hour(s) of AMA PRA category 1 credit
Pharmacists - up to 1.5 contact hour(s) (0.15 CEUs)
New and Investigational Antiretroviral Drugs
Mark A. Wainberg, PhD
Treatment Failure and Antiretroviral Management of Treatment-Experienced Patients
Julio S.G. Montaner, MD, FRCP
Marianne Harris, MD
Novel Treatment Strategies
Douglas J. Ward, MD
HIV Drug Resistance and Pharmacology CME
Physicians - up to 1.0 hour(s) of AMA PRA category 1 credit
Pharmacists - up to 1.0 contact hour(s) (0.1 CEUs)
Antiretroviral Drug Resistance and Viral Fitness
Stefano Vella, MD
Advances in the Clinical Pharmacology of Antiretroviral Therapy
Praphan Phanuphak, MD, PhD
Complications of HIV Disease and Therapy CME
Physicians - up to 1.0 hour(s) of AMA PRA category 1 credit
Pharmacists - up to 1.0 contact hour(s) (0.1 CEUs)
Etiology and Management of Morphologic Changes Associated With HIV Infection and Antiretroviral Therapy (includes an update from the 5th International Workshop on Adverse Reactions and Lipodystrophy in HIV)
Graeme J. Moyle, MD, MBBS
Antiretroviral Influences on Atherosclerosis and Fat Metabolism (includes an update from the 5th International Workshop on Adverse Reactions and Lipodystrophy in HIV)
Mark A. Wainberg, PhD
Opportunistic Infections: Little Attention to the Big Killers
Pedro Cahn, MD, PhD
Pathogenesis of HIV Infection CME
Physicians - up to 0.5 hour(s) of AMA PRA category 1 credit
Virus and Host Factors in HIV Pathogenesis
Jay A. Levy, MD
HIV Immunopathogenesis and Correlates of Protection
Bruce Walker, MD
HIV Disease in Children CME
Physicians - up to 0.5 hour(s) of AMA PRA category 1 credit
Treatment of HIV Infection in Children
Stephane Blanche, MD

 
Expert Commentary and Interviews
This Just in... Late-Breaker Session 1
July 17, 2003
Read about primary drug resistance, switch therapy, preventing mother-to-child HIV transmission via breastfeeding, and more in this roundup of late breakers from Brian Conway, MD.
This Just in... Late-Breaker Session 2
July 17, 2003
Douglas J. Ward, MD, digests the latest information on adherence and resistance, and on the next wave of investigational drugs.
Expert Commentary: Scaling Up ART for Developing Countries -- We Can Walk and Chew Gum at the Same Time
July 16, 2003
Mauro Schechter, MD, PhD, comments on present and planned treatment access initiatives in the developing world vis-à-vis the Brazilian experience.
Expert Commentary: Should Treatment for HIV Be Based on Results of Clinical Trials More Than on Viral Pathogenesis?
July 16, 2003
Brian Conway, MD, comments and provides relevant illustrations to an expert debate on the relative importance of evidence-based and principle-driven approaches to the optimal management of HIV infection.
Expert Commentary: Enfuvirtide: Durability Despite Injection Requirements
July 16, 2003
Graeme Moyle, MD, MBBS, reports on the 48-week results of the TORO studies, which indicate that enfuvirtide can be administrated durably and with sustained effects in heavily pretreated patients.
Expert Commentary: Treatment Interruption Update
July 16, 2003
Douglas J. Ward, MD, comments on the pros and cons of treatment interruption, per the latest data and expert opinions presented at the 2nd IAS Conference.
Expert Commentary: Viral Dynamics and Fitness
July 15, 2003
Mark A. Wainberg, PhD, comments on the session discussing viral dynamics and fitness. It is clear that advances in these areas, notably receptor usage, viral quantification, and genetic diversity, will influence treatment in the near future.
Expert Commentary: HIV Drug Resistance Update
July 14, 2003
Mark A. Wainberg, PhD, provides an insightful overview of new data and evolving knowledge pertaining to the development, detection, and clinical significance of antiretroviral drug resistance.
Expert Commentary: HAART -- Making a Good Thing Better
July 14, 2003
Brian Conway, MD, reports on new directions in antiretroviral therapy.
Expert Commentary: Complications of Antiretroviral Therapy
July 14, 2003
Douglas J. Ward, MD, reports on the newest clinical information on lipodystrophy and other treatment-related health risks.
Expert Commentary: Opening Ceremony
July 13, 2003, Paris
Mark A. Wainberg, PhD, comments on the opening session of IAS 2003. The message: expanding antiretroviral drug access in the developing world is a moral, ethical, and economic imperative following 20 years of advances in the study and treatment of HIV disease in the United States and Europe.

 
Downloads
Downloadable PowerPoint Slide Set:
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Selected Posters & Abstracts Coverage

 
International Perspectives
Developed in collaboration with our international partners.
Mexico Canada
Mexico Mexico
Selected Translations

 
Daily Conference News from Medscape HIV/AIDS
Read daily conference news from Medscape Medical News, Reuters Health, and World AIDS News.
Enfuvirtide Effective in Suppressing HIV for One Year 7/17/03
[Medscape Medical News]
More than 30% of patients receiving the drug, formerly known as T-20, achieved a more than 90% reduction in viral load levels.
Intermittent HIV Treatment Proves Disappointing 7/17/03
[Medscape Medical News]
But scheduled drug regimen switching appears to work.
Treatment of Mothers and Children Greatly Reduces HIV Transmission to Newborns 7/17/03
[Medscape Medical News]
Six months after birth, more than 90% of the infants are free of HIV, African researchers said.
Breast Feeding Looks Possible With Prophylaxis 7/17/03
World AIDS News by Mark Mascolini
Reality Check: What Happens Without HAART 7/17/03
World AIDS News by Mark Mascolini
New Drugs Offer Hope to HIV Patients With Few Options 7/16/03
[Medscape Medical News]
The protease inhibitor atazanavir and the fusion inhibitor enfuvirtide show promise in treatment-experienced patients.
Antiretroviral Holidays Tied to Clinical Progression 7/16/03
World AIDS News by Mark Mascolini
Total T-Cell Count Questioned as CD4 Stand-in 7/16/03
World AIDS News by Mark Mascolini
Revised Guidelines for HIV/AIDS Treatment: A Newsmaker Interview With John G. Bartlett, MD 7/15/03
[Medscape Medical News]
Based on results of clinical trials and expert opinions, the guidelines identify preferred regimens, which should simplify and improve the initial approach to treatment.
Attempt to Make AIDS Therapy Simpler Runs Into a Clinical Trial Roadblock 7/15/03
[Medscape Medical News]
Patients infected with human immunodeficiency virus (HIV) would likely be more compliant with long-term therapy if they didn't have to take complicated multidrug regimens to achieve adequate suppression of the virus in their blood.
Virologic Failure of Trizivir Versus Efavirenz Combos 7/15/03
World AIDS News by Mark Mascolini
Drug Breaks After Acute Infection: Success or Failure? 7/15/03
World AIDS News by Mark Mascolini
Keynote Rebuts Barriers to HIV Therapy in Developing World 7/14/03
[Medscape Medical News]
The scaling up of anti-HIV initiatives was the theme of the opening session of the Second IAS Conference on HIV Pathogenesis and Treatment.
IAS Meeting Starts With Focus on AIDS Drug Access 7/14/03
World AIDS News by Mark Mascolini

 
20 Years of HIV Science
The following articles are part of a Nature Medicine special issue, "20 Years of HIV Science." The entire issue is available free for a limited time on the Nature Medicine Web site.
Special Presentations: Keynotes, Plenary Addresses, and Selected Sessions
Wednesday, July 16, 2003
Main Plenary
View Webcast

Chairs: Jean-François Delfraissy and Douglas Richman

bullet HIV Entry: Insights Into Viral Tropism, Pathogenesis, and Antiviral Therapy
Robert Doms
University of Pennsylvania, Philadelphia


bullet Mechanisms and Management of Metabolic Complications Associated With Highly Active Antiretroviral Therapy
Peter Reiss
Academic Medical Center, University of Amsterdam, The Netherlands


Closing Ceremony
View Webcast
Tuesday, July 15, 2003
Main Plenary
View Webcast

Chairs: Christine Katlama and Giuseppe Pantaleo

bullet New Antiretroviral Drugs and Therapeutic Strategies
Patrick Yeni
Hospital Bichat, Paris, France


bullet HIV Vaccine Research: The State of the Science
Lawrence Corey
University of Washington, Seattle

Controversy: There Is More Risk Than Value in Treatment Interruptions
View Webcast

Forum: The Scaling-up of Antiretroviral Therapy in Developing Countries
View Webcast

bullet Update on the Use of Antiretrovirals in Countries With Limited Resources: From Pilot Studies to Public Health Realities
Papa Salif Sow
Dakar University Teaching Hospital, Senegal

bullet The Challenges of Expanding Access to Antiretrovirals Worldwide
Paulo Teixeira
Brazilian STD/AIDS Program, Ministry of Health, Brasilia, Brazil

Additional Forum participants: Sanjay Pujari, E. Shutes, Sarah A. Adomakoh, and N. Durier.
Monday, July 14, 2003
Main Plenary
View Webcast

Read Transcript

Chairs: Françoise Barré-Sinoussi and Souleymane Mboup

bullet Challenges and Lessons Learned in Implementing Antiretroviral Therapy in the Developing World
Ernest Darkoh
Ministry of Health, Gaborone, Botswana

bullet Host/Virus Mechanisms in the Molecular Pathogenesis of HIV
Nathaniel R. Landau
The Salk Institute for Biological Studies, San Diego, California

Extraordinary Plenary: 20 Years of HIV Science
View Webcast

Read Transcript

Chairs: Robert C. Gallo, Institute of Human Virology, University of Maryland, Baltimore; and Luc Montagnier, Fondation Mondiale Recherche et Prevention SIDA, Paris, France.

bullet Keynote lecture
20 Years of HIV Science
Anthony Fauci
Director NIAID, NIH, Bethesda, Maryland

Keynote address
From Science to Action: Challenges in Managing AIDS
Nelson Mandela
Former President of South Africa
Sunday, July 13, 2003
Chairs: Michel Kazatchikine and Joep Lange. Bertrand Delanoe, Mayor of Paris, also speaks.

bullet Keynote opening address
Building a State-Civil Society Alliance to Fight AIDS: The Brazilian Experience
Fernando Henrique Cardoso, former President of Brazil

bullet Keynote lecture
Expanding Access to Antiretroviral Treatment in the Developing World: The Economic Rationale
Jean-Paul Moatti
University of the Mediterranean, Marseille, France

bullet Community address
Where Is the War Chest Against AIDS?
Marie-Josée Mbuzenakamwe
Association Nationale de Soutien aux Séropositifs et Sidéens (ANSS), Bujumbura, Burundi
These and other Conference Webcasts are available at kaisernetwork.org

 
Legal Disclaimer
The materials presented here were prepared by independent authors under the editorial supervision of Medscape, and do not represent a publication of the International AIDS Society. These materials and the related activity are not sanctioned by the International AIDS Society or the commercial supporter of the conference, and do not constitute an official part of that conference.
The material presented here does not reflect the views of Medscape or the companies providing unrestricted educational grants. These materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified health care professional should be consulted before using any therapeutic product discussed. All readers or continuing education participants should verify all information and data before treating patients or employing any therapies described in this educational activity.
Copyright © 2003 Medscape.

 


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