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Perspective

  • Targets for Treating Renal Aging Dr O'Sullivan, the lead author of a study published in the Journal of the American Society of Nephrology, discusses his findings and theories on the causes and consequences of renal aging.
  • Assessing Stroke Risk in Adult Congenital Heart Disease   Drs Lyle, Ammash, and McLeod discuss risk stratification for stroke in adults with complex congenital heart disease and how to choose between warfarin or the direct oral anticoagulants in the absence of data.
  • Alt FOURIER: Diet and Exercise vs PCSK9i?   If Dr Walton-Shirley were designing the next trial on PCSK9 inhibitors, she'd include a Mediterranean diet and exercise arm. She and Dr Mandrola ponder alternative uses of our healthcare dollars.
  • FOURIER Presenter, Dr Marc Sabatine, Interviewed   Dr Mandrola gets the details on the PCSK9 inhibitor evolocumab, and asks the $64,000 (or is that $14,000) question about cost-effectiveness.