Clinical cardiology news, opinions and education

heartwire News

  • Most European Heart Failure Patients Undertreated, Risk Death Most heart failure patients in Europe don’t get the recommended medication doses, and those who don’t seem to be at greater risk of death or hospitalization than those who do, researchers say.
  • ACC Fewer Bleeds on Uninterrupted Dabigatran vs Warfarin in AF Ablation "Now we have high-quality data showing that if you perform this procedure on uninterrupted dabigatran, the risk of stroke is extremely low," said a researcher about the randomized RE-CIRCUIT trial.
  • EAU Testosterone Tie to Cardiovascular Disease Loosened A study of nearly 7000 patients is easing fears about testosterone replacement therapy increasing the risk for cardiovascular disease and thromboembolic events, but concerns about sleep apnea linger.
  • ACC No Plaque Reduction Seen With Mimetic HDL Agent in ACS The study in patients with ACS did nothing to support the HDL hypothesis, although the bioengineered agent meant to promote reverse cholesterol transport had been promising in prior studies.

Perspective

  • Migraine Linked to Cervical Artery Dissection This is the second large study to find such an association, but the first to identify it as being stronger in young patients. Dr Laurie Barclay shares the results.
  • Targets for Treating Renal Aging Dr O'Sullivan, the lead author of a study published in the Journal of the American Society of Nephrology, discusses his findings and theories on the causes and consequences of renal aging.
  • Assessing Stroke Risk in Adult Congenital Heart Disease   Drs Lyle, Ammash, and McLeod discuss risk stratification for stroke in adults with complex congenital heart disease and how to choose between warfarin or the direct oral anticoagulants in the absence of data.
  • Alt FOURIER: Diet and Exercise vs PCSK9i?   If Dr Walton-Shirley were designing the next trial on PCSK9 inhibitors, she'd include a Mediterranean diet and exercise arm. She and Dr Mandrola ponder alternative uses of our healthcare dollars.