Chronic Leukemia

Chronic Leukemia News

  • Alemtuzumab-Methylprednisolone in CLL With TP53 Deletion Alemtuzumab plus methylprednisolone was very effective at putting chronic lymphocytic leukemia (CLL) into remission in patients with TP53 deletion (17p-), in a mid-stage trial in the UK.
  • EPOCH-Rituximab With Fludarabine a Useful Bridge to HSCT For patients with aggressive lymphoid malignancies, EPOCH-rituximab with fludarabine can be an effective bridge to reduced-intensity conditioning and allogeneic hematopoietic stem-cell transplantation.
 

Chronic Leukemia Perspectives

  • Great New Drugs Will Be Harder to Come By Great New Drugs Will Be Harder to Come By   Dr. Bruce Cheson discusses the Cheson Rule for New Drug Approval, which states (rather paradoxically) that the more effective a drug is, the more it negatively affects future drug development.
  • A Dickensian CLL Story   Drs. Bruce Cheson and Clemens Wendtner visit ghosts of CLL treatment past, present, and future.
 

Journals

 
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