Chronic Leukemia

Chronic Leukemia News

  • New Class of Drug May Vanquish CLL New Class of Drug May Vanquish CLL The novel small molecule navitoclax blocks the function of Bcl-2, a protein essential for the growth of chronic lymphocytic leukemia cells, and may represent a "revolution" in the treatment of CLL.
    Medscape Medical News, December 29, 2011
  • Massive Hunt Finds New Mutations That Drive CLL ASH Massive Hunt Finds New Mutations That Drive CLL Massive parallel sequencing has identified 9 genes that play a role in the pathogenesis of CLL, including 5 novel mutated genes that are implicated for the first timer.
    Medscape Medical News, December 12, 2011
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Chronic Leukemia Perspectives

  • Great New Drugs Will Be Harder to Come By Great New Drugs Will Be Harder to Come By   Dr. Bruce Cheson discusses the Cheson Rule for New Drug Approval, which states (rather paradoxically) that the more effective a drug is, the more it negatively affects future drug development.
    Medscape Hematology-Oncology, December 29, 2011
  • A Dickensian CLL Story   Drs. Bruce Cheson and Clemens Wendtner visit ghosts of CLL treatment past, present, and future.
    Medscape Hematology-Oncology, December 23, 2011
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