Neurology News

  • Novel Protein Signals Rapid Hippocampal Atrophy in AD People with an intermediate or high likelihood of having Alzheimer's disease who had TDP-43 in the hippocampus had a faster rate of hippocampal atrophy than did those with no TDP-43.
 
  • WCN Cardiac Effects of Fingolimod in MS Reversible Fingolimod, used to treat multiple sclerosis, dampens cardiac autonomic modulation at rest and during challenges, but this effect appears to be reversible after discontinuation of the drug, a study shows.
  • cc-ihs CGRP Monoclonals: Safe, Effective for Migraine in Phase 3 Trials Four development-stage monoclonal antibodies, acting on the calcitonin gene-related peptide pathway, showed good efficacy and safety in the treatment or prevention of migraine.
  • Dietary Supplement With Ketones May Mitigate Migraine Attacks Among patients with migraine, daily dietary supplementation with ketones raised blood ketone levels and reduced the monthly number of attacks by half, preliminary trial results have shown.
  • High, Low Magnesium Levels Linked to Dementia Risk Findings that both low and high levels of serum magnesium were associated with increased risk for all-cause dementia suggest a U-shaped relationship, note investigators.
 

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  • Biologics Not Linked to Higher Cancer Risk in RAPatients with RA treated with biologic drugs had no overall increase in cancer risk compared with similar patients treated with conventional DMARDs, a study of nearly 70,000 patients has found.
  • Cardiac Effects of Fingolimod in MS ReversibleFingolimod, used to treat multiple sclerosis, dampens cardiac autonomic modulation at rest and during challenges, but this effect appears to be reversible after discontinuation of the drug, a study shows.
  • Novartis's Rydapt Wins EU Approval for AML, Other DiseasesSwiss drugmaker Novartis on Wednesday won European Union approval for Rydapt to be used against a mutated form of acute myeloid leukemia (AML) and other rare diseases, adding to U.S. approvals the medicine secured in April.
  • Sen McCain's 'No' Vote Threatens Graham-Cassidy BillLike many medical societies and other healthcare groups, the senator said he couldn't vote yes for the bill without seeing a CBO report on how it would affect healthcare coverage and insurance premiums.

Perspective

Business of Medicine

  • Should Physicians Educate Patients via Social Media?   More patients are going online to get health information and some of the information on the Internet is not scientific. What can physicians do to educate patients via social media?
  • How Residents Cope: Bingeing, Drinking, Sports, and Friends Overeating. Drinking. Antidepressants. These are a few of the coping mechanisms residents rely on to get through their stressful residencies. Are there any positive coping strategies?

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Medscape Editor-in-Chief

  • Eric J. Topol, MD Eric J. Topol, MD Director, Scripps Translational Science Institute; Chief Academic Officer, Scripps Health; Professor of Genomics, The Scripps Research Institute; Senior Consultant, Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, California; Editor-in-Chief, Medscape