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Rapamycin Treatment for a Child With Germline PTEN Mutation
Proteus syndrome is a rare hamartoma syndrome characterized by germline PTEN mutations. How effective is oral rapamycin therapy for its treatment?
Journal Article, June 2008
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Fostering Multidisciplinary Cancer Care in a Community Setting
Dr. Ralph Boccia, a community oncologist, speaks with Dr. Michael Choti, a renowned liver surgeon, about the realities and challenges of delivering multidisciplinary cancer care in the community.
Expert Viewpoint, May 2008
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The NCCN Clinical Practice Oncology Forum: Harnessing the Power of Online Education
Dr. Robert Carlson announces an exciting new collaboration between the NCCN and Medscape Oncology to develop CME programming that will be relevant to all oncologists, regardless of expertise.
Article, May 2008
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CME
HIV Pharmacogenomics (Slides With Audio)
Dr. David Back discusses HIV pharmacogenomics at the 2008 New York Course.
Slide/Lecture Presentation, May 2008
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CME
Diagnosis and Management of Advanced Hepatocellular Carcinoma
This interactive case illustrates the complexity of treating hepatocellular carcinoma and highlights the latest treatment options and guidelines.
Clinical Case, May 2008
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From Blockbuster Medicine to Personalized Medicine
Will "big pharma" be able to develop and deliver drugs that fit the individual patient's biology and pathophysiology?
Journal Article, May 2008
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Rapid Identification of Methicillin-Resistant Staphylococci Bacteremia Among Intensive Care Unit Patients
Four rapid methods were evaluated directly from positive blood cultures in parallel for identification of methicillin-resistant Staphylococcus aureus (MRSA) and MR-coagulase-negative staphylococci.
Journal Article, May 2008
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CME/CE
A Puzzling Facial Rash on a 17-Year-Old Boy
A 17-year-old boy presents to the pediatric infectious disease clinic with a 10-day history of a facial rash. The rash began as several pimples over the forehead and cheek that spread to most of the right side of his face. The lesions are not itchy, but they are painful. No improvement was noted with 2 separate courses of antibiotic therapy. The patient is very active on his school wrestling team, and he was happily preparing for an upcoming competition. What is the most likely diagnosis?
Clinical Case, May 2008
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Word Use and Semantics in Alternative Medicine: A Survey of Editors of Medical and Related Journals
This original article investigates the views, practices, and policies of medical journal editors on the use of words and phrases present in alternative medicine manuscripts submitted for publication.
Journal Article, May 2008
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CME/CE
Ear Pain and a Rash in a 24-Year Old Man
A 24-year-old man with HIV presents to the ED with intensifying left ear pain, swelling, and dizziness. His hearing in his left ear is muffled compared to that in his right ear. There is no history of trauma or allergic reactions, and the patient does not take any medications. The physical examination is notable for an obviously erythematous and edematous left ear, as well as a subtle left facial droop and weakness. What is the diagnosis?
Clinical Case, May 2008
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Predicting recurrence in patients with high-risk early-stage epithelial ovarian cancer
In this VideoBlog, Dr. Maurie Markman notes that the findings of this study may be particularly useful in discussions with patients about the advisability of further treatment.
Expert Viewpoint, May 2008
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CME/CE
Recurrent Bacteremia in a 73-Year-Old Woman
An elderly woman presents to the ED with fever, chills, and night sweats. The patient was recently hospitalized for hematochezia and fever; blood and urine cultures at that time showed evidence of bacteremia, and she was therefore treated with a course of levofloxacin. Over the past 24 hours, the fever and chills have returned. Her past medical history includes aortobifemoral bypass graft surgery and coronary artery bypass graft surgery. What is the diagnosis?
Clinical Case, May 2008
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The Case of the Ruthless Ruler With a Deadly Disease
Guess this unpopular leader and diagnose his condition in another historical case from this popular series.
Clinical Case, May 2008
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Physicians: Organize for High Performance
Anthony Shih, MD, MPH, Assistant Vice President, Quality Improvement and Efficiency, The Commonwealth Fund, New York, explains why US healthcare delivery systems should be revamped.
Editorial, May 2008
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What is the value of recommended cervical cancer screening?
In this videoblog, Dr. Maurie Markman discusses an important study demonstrating the utility of recommended cervical cancer screening, not only for identifying early lesions but also for discovering cases of advanced disease
Journal Article, May 2008
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CME/CE
Back Pain in a 39-Year-Old Man from Guatemala
A 39-year-old Guatemalan man presents to the ED with severe and debilitating back pain. He has been previously evaluated for his back pain twice in the past few weeks. The pain is throbbing and diffuse throughout the lower back, with radiation to his left buttock and upper back, and it has been progressively worsening. Mild tenderness to palpation is noted in the midline lower back. A lumbar radiograph and a magnetic resonance imaging scan of the spine are obtained. What is the diagnosis?
Clinical Case, May 2008
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Occult Tumor Cells in Colorectal Cancer: Is There an Effect on Survival After Curative Surgery?
Commentary on a study on occult tumor cells and colorectal cancer, published February 2008 in the Archives of Surgery.
Expert Viewpoint, May 2008
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Why the NIH Trial to Assess Chelation Therapy (TACT) Should Be Abandoned
The $30 million, NIH Phase 3 Trial to Assess Chelation Therapy (TACT) exposes subjects to a risky method that is known to be ineffective. The TACT should be abandoned and its origins investigated.
Journal Article, May 2008
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What Are the Risks of Contracting MRSA From Domesticated Animals?
Is there a risk of contracting MRSA from domesticated animals? An expert answers a reader's question about disease transmission from animals to humans.
Expert Viewpoint, May 2008
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Infectious Syphilis: The Return of an Epidemic
An infectious syphilis epidemic returns to challenge public health. As past becomes present, what do clinicians need to know about this sexually transmitted infection?
Expert Viewpoint, May 2008
