Colorectal Cancer Resource Center Features

• Colon Cancer Screening: Is It Only a Swallow Away?   Will colon capsule endoscopy replace colonoscopy for colorectal cancer screening? David A. Johnson, MD, discusses the pros and cons of this emerging technology in his latest video blog.
  Medscape Gastroenterology, August 2009
• Endoscopy: Insertion Versus Withdrawal Phases for Polyp Detection Colonoscopic polyp detection is commonly performed during slow withdrawal of the colonoscope. A new study suggests further investigation of polyp inspection during the insertion phase is warranted.
  Nature Reviews Gastroenterology & Hepatology, August 2009
• Predicting Response to Cetuximab Via Circulating Tumor Cells in Metastatic Colorectal Cancer Dr. Maurie Markman comments on a study published in Clinical Cancer Research demonstrating the use of KRAS in circulating tumor cells to predict response to cetuximab in patients with mCRC.
  Medscape Genomic Medicine, July 2009
• Laparoscopic Versus Open Surgery for Rectal Cancer: Long-Term Oncologic Results How do long-term results compare for these two approaches in rectal cancer?
  Annals of Surgery, July 2009
• Prognostic Significance of Mast Cell Number and Microvascular Density for the Survival of Patients With Primary Colorectal Cancer This study aimed to assess the mast cell and microvessel densities in the invasive colorectal cancers and to determine their prognostic relevance for survival of the patient with colorectal carcinoma.
  Journal of Gastroenterology and Hepatology, July 2009
• Comparison of Treatment Received Versus Long-Standing Guidelines for Stage III Colon and Stage II/III Rectal Cancer Patients Diagnosed in Alberta, Saskatchewan, and Manitoba in 2004 This study measured adherence to guideline-recommended treatments for stage II/III colorectal cancer across 3 Canadian provinces and assessed patient characteristics and receipt of standard care.
  Clinical Colorectal Cancer, July 2009
• Can FDG PET-CT Detect the Primary Cause of Ascites? Commentary on a study on the role of FDG PET-CT in the differential diagnosis of ascites, published April 2009 in the Journal of Nuclear Medicine.
  Medscape Radiology, June 2009
• Inhibition of STAT5 Induces G1 Cell Cycle Arrest and Reduces Tumor Cell Invasion in Human Colorectal Cancer Cells Could STAT5 signaling be targeted in colorectal cancer?
  Laboratory Investigation, June 2009
• Risk of Colorectal Cancer Seven Years After Flexible Sigmoidoscopy Screening: Randomised Controlled Trial What is the effect of screening with flexible sigmoidoscopy on the incidence of colorectal cancer after a minimum of 6 years of follow-up?
  BMJ (Clinical research ed.), May 2009
• Are Serrated Polyps Markers for Advanced Colorectal Neoplasia? What is the malignancy potential of large serrated polyps? Could they be associated with elevated risk for synchronous advanced colorectal neoplasia?
  Journal Watch, May 2009
• Highlights of the 2009 Colon Cancer Screening Guidelines From the American College of Gastroenterology -- What You Need to Know Topping the list of preferred strategies for colon cancer screening is quality colonoscopy.
  Medscape Gastroenterology, May 2009
• Colorectal Cancer Screening: Both Over- and Underused Is colorectal cancer screening reaching older eligible patients, and is screening targeted to patients who are expected to live long enough to benefit from it?
  Journal Watch, May 2009
• ASCO 2009: New Findings Could Be Practice-Changing In this video blog, Dr. John Marshall speculates about the 2009 ASCO meeting, focusing on molecular profiling and adjuvant treatment for CRC as well as on a new treatment for upper GI cancers.
  Medscape Hematology-Oncology, May 2009
• Is the Presence of GUCY2C Associated With Recurrence and Survival in Patients With Colorectal Cancer? Commentary on a study on the association of occult lymph node metastases detected by GUCY2C with survival in patients with colorectal cancer, published February 2009 in JAMA.
  Medscape General Surgery, May 2009
• CT Colonography to Screen for Colorectal Cancer and Aortic Aneurysm in the Medicare Population: Cost-Effectiveness Analysis What are the potential clinical efficacy and cost-effectiveness of CT colonography for colorectal cancer screening in the Medicare population relative to both optical colonoscopy and no screening?
  American Journal of Roentgenology, May 2009
• Highlights of 2009 Colon Cancer Screening Guidelines In this video blog, David A. Johnson, MD, FACG, FASGE, FACP presents an overview of the new guidelines issued by the American College of Gastroenterology for colorectal cancer screening.
  Medscape Gastroenterology, April 2009
• Factors Influencing Choices for Colorectal Cancer Screening Among Previously Unscreened African and Caucasian Americans: Findings From a Triangulation Mixed Methods Investigation What are the preferred colorectal cancer screening methods among adults with varied race, gender, and geographic region demographics?
  Journal of Community Health, April 2009
• Digestive Cancer in the Elderly This article reviews data for treatment of digestive cancers in the elderly, whether such patients have less tolerance to antineoplastic therapies or have poorer outcomes than younger patients.
  Cancer & Chemotherapy Reviews, April 2009
• Current Management of Colorectal Hepatic Metastasis Modern management of hepatic colorectal metastases necessitates a multidisciplinary approach to effectively treat affected patients and increase the number of patients who will benefit from resection.
  Expert Review of Gastroenterology and Hepatology, April 2009
• When Two Targeted Therapies Are Not Better Than One In this video blog, Dr. Maurie Markman emphasizes the importance of conducting phase 3 trials to evaluate promising new concepts. Sometimes, what we hope will happen just doesn't pan out.
  Medscape Hematology-Oncology, March 2009