Respiratory Research is an Open Access, peer-reviewed, online journal that considers manuscripts on all aspects of respiratory function and disease.
The journal welcomes studies on asthma, chronic obstructive pulmonary disease, cystic fibrosis, genetics, infectious diseases, interstitial lung diseases, lung development, lung tumors, occupational and environmental factors, pulmonary circulation, pulmonary pharmacology and therapeutics, respiratory critical care, respiratory immunology, respiratory physiology, and sleep. The journal will also welcome state-of-the-art reviews on related topics.
-
Assessment of Pulmonary Antibodies With Induced Sputum and Bronchoalveolar Lavage Induced by Nasal Vaccination Against Pseudomonas Aeruginosa: A Clinical Phase I/II Study
Does nasal vaccination against Pseudomonas aeruginosa i as a prevention of airway infection in patients with cystic fibrosis work?
Journal Article, August 2007
-
Comparison of the Effects of Salmeterol/fluticasone Propionate with Fluticasone Propionate on Airway Physiology in Adults With Mild Persistent Asthma
Is combinaiton threapy benifical for airway resistance in mild asthmatics with near normal FEV1 values?
Journal Article, July 2007
-
IL-13-induced Proliferation of Airway Epithelial Cells: Mediation by Intracellular Growth Factor Mobilization and ADAM17
IL-13 was found to induce NHBE cell proliferation, and release of TGFá, in an ADAM17-dependent manner; however, this IL-13-induced proliferation did not appear to result solely from ADAM17 activation.
Journal Article, July 2007
-
Phenotypic Alterations in Type II Alveolar Epithelial Cells in CD4+ T Cell Mediated Lung Inflammation
This article looks at a model to assess the inflammatory mediators expressed by alveolar epithelial target cells triggered by antigen-specific recognition in CD4+ T cell-mediated lung inflammation.
Journal Article, July 2007
-
Efficacy and Safety of Tiotropium in COPD Patients in Primary Care - The SPiRiva Usual CarE (SPRUCE) Study
What impact does introducing tiotropium have on outcomes in patients with COPD?
Journal Article, July 2007
-
Control of Mucosal Virus Infection by Influenza Nucleoprotein-Specific CD8+ Cytotoxic T Lymphocytes
This data suggests that influenza NP-specific CD8+ CTL can play a direct role in clearance of influenza virus from the upper respiratory mucosal surfaces.
Journal Article, June 2007
-
A Novel Human Ex Vivo Model for the Analysis of Molecular Events During Lung Cancer Chemotherapy
Does a a short-term tissue culture model provide a useful human model to study numerous aspects of mechanisms underlying tumor responsiveness towards improved anticancer treatments?
Journal Article, June 2007
-
Body Mass Index is Associated with Reduced Exhaled Nitric Oxide and Higher Exhaled 8-Isoprostanes in Asthmatics
Do body mass index related changes in exhaled NO differ between asthmatics and controls, and are these related to increased airway oxidative stress and systemic levels of leptin and adiponectin?
Journal Article, April 2007
-
Clinical Implications for Vascular Endothelial Growth Factor in the Lung: Friend or Foe?
VEGF is one of the most potent mediators of vascular regulation in angiogenesis and vascular permeability to water and proteins. What role does it play in lung disease? Should we be concerned?
Journal Article, October 2006
-
Role of TNFalpha in Pulmonary Pathophysiology
Anti-TNFalpha therapeutic strategies represent an important breakthrough in the treatment of inflammatory diseases and may have a role in treating pulmonary disease.
Journal Article, October 2006
-
Airway Smooth Muscle as a Target of Asthma Therapy: History and New Directions
A review of excitation-contraction coupling in ASM with a discussion on the current treatment of asthma.
Journal Article, September 2006
-
Differences in MAP Kinase Phosphorylation in Response to Mechanical Strain in Asthmatic Fibroblasts
A look at the phenotypic differences in MAP kinase phosphorylation in asthmatic patients and normal controls reveal that different signaling pathways are involved in transducing mechanical stimuli.
Journal Article, April 2006
-
Toll-Like Receptors in Cellular Subsets of Human Tonsil T Cells: Altered Expression During Recurrent Tonsillitis
An examination of the TLR expression in T cells from patients with recurrent tonsillitis and tonsillar hyperplasia.
Journal Article, February 2006
-
Lung Fibroblasts From Patients with Emphysema Show Markers of Senescence in Vitro
A comparison of cellular senescence markers and expression of respective genes between lung fibroblasts from patients with emphysema and control patients without COPD.
Journal Article, February 2006
