Journal of Neuroinflammation
Journal of Neuroinflammation is an Open Access, peer-reviewed online journal that focuses on innate immunological responses of the central nervous system, involving microglia, astrocytes, cytokines, chemokines, and related molecular processes.
'Neuroinflammation' is an encapsulization of the idea that microglial and astrocytic responses and actions in the central nervous system have a fundamentally inflammation-like character, and that these responses are central to the pathogenesis and progression of a wide variety of neurological disorders. This idea has revolutionized our understanding of Alzheimer's disease, where it originated, and now has applications to other neurodegenerative diseases, to ischemic/toxic diseases, and even to normal brain development. Neuroinflammation incorporates a wide spectrum of complex cellular responses that include microglia and astrocytes, cytokines and chemokines, complement proteins, acute phase proteins, oxidative injury, and related molecular processes.
Neuroinflammation is a new and rapidly expanding field that has revolutionized our understanding of chronic neurological diseases. This field has grown to encompass researchers with backgrounds in many diverse fields, including pathology, biochemistry, molecular biology, genetics, clinical medicine, and epidemiology. Important contributions to this field have come from work with populations, with patients, with postmortem tissues, with animal models, and with in vitro systems. The Journal of Neuroinflammation will bring together work focusing on common pathogenic processes, and provide a forum for integrative reviews and commentaries on this field.
About Journal of Neuroinflammation
Editorial Board Author Guidelines Manuscript Submissions Reprint Information- Resveratrol Inhibits Prostaglandin Formation in IL-1beta-stimulated SK-N-SH Neuronal Cells
- Neuroinflammation and MMPs: Potential Therapeutic Targets in Neonatal Hypoxic-ischemic Injury
- Functional Interleukin-17 Receptor A Is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune Encephalomyelitis
- Acetaminophen Inhibits Neuronal Inflammation and Protects Neurons From Oxidative Stress
- Microglial Inhibition of Neuroprotection by Antagonists of the EP1 Prostaglandin E2 Receptor
- Differential Effects of Th1, Monocyte/Macrophage and Th2 Cytokine Mixtures on Early Gene Expression for Molecules Associated With Metabolism, Signaling and Regulation in Central Nervous System Mixed Glial Cell Cultures
- Antiphospholipid Antibodies: Paradigm in Transition
- Expression and Distribution of Toll-Like Receptors 11-13 in the Brain During Murine Neurocysticercosis
- Impact of Innate Immunity in a Subset of Children With Autism Spectrum Disorders: A Case Control Study
- TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease
- Apigenin and Luteolin Modulate Microglial Activation Via Inhibition of STAT1-Induced CD40 Expression
- Neuro-Inflammation Induced By Lipopolysaccharide Causes Cognitive Impairment Through Enhancement Of Beta-Amyloid Generation
- Immune Modulation And Increased Neurotrophic Factor Production In Multiple Sclerosis Patients Treated With Testosterone
- Suppression of Acute Proinflammatory Cytokine and Chemokine Upregulation by Post-injury Administration of a Novel Molecule Improves Long-term Neurologic Outcome in Model of Traumatic Brain Injury
- The Synthetic Triterpenoid CDDO-Methyl Ester Modulates Microglial Activities, Inhibits TNF Production, And Provides Dopaminergic Neuroprotection
- Exercise Alters The Immune Profile In Tg2576 Alzheimer Mice Toward A Response Coincident With Improved Cognitive Performance And Decreased Amyloid
- Plaque Complement Activation and Cognitive Loss in Alzheimer's Disease
- The Role Of Interleukin-1 In Neuroinflammation And Alzheimer Disease: An Evolving Perspective
- Perispinal Etanercept: Potential As An Alzheimer Therapeutic
- Rapid Cognitive Improvement In Alzheimer's Disease Following Perispinal Etanercept Administration