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Celecoxib No Clinical Utility as Chemopreventive Agent, Experts Say
They also warn that new trials studying the well-known pain reliever in high doses would be unethical.
Medscape Medical News, May 2008
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CME
Long-Term Breast-Feeding May Reduce Risk for Rheumatoid Arthritis
A study shows that long-term breast-feeding (more than 1 year), but not oral contraceptive use, is associated with a significant reduction in the risk for rheumatoid arthritis.
Medscape Medical News, May 2008
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Patients' Perception of Symptoms Influences Use of Wrist Working Splints
Whether or not patients with rheumatoid arthritis (RA) use wrist working splints is largely dependent on the seriousness of the perceived symptoms, according to study findings published in the April 15th issue of Arthritis and Rheumatism.
Reuters Health Information, May 2008
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Trauma and Certain Exposures Linked to the Onset of Arthritis in Psoriasis
A number of environmental exposures, including trauma, are associated with the onset of inflammatory arthritis in patients with psoriasis, findings published in the May issue of the Annals of the Rheumatic Diseases indicate.
Reuters Health Information, May 2008
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Anti-TNF Therapy "Viable Alternative" for Rheumatic Disease in HIV Patients
HIV-positive individuals with rheumatic disease can be effectively treated with anti-tumor necrosis factor (TNF) agents, according to a report in the May issue of the Annals of the Rheumatic Diseases.
Reuters Health Information, May 2008
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MRI Shows Frequent Temporomandibular Joint Involvement in Juvenile Arthritis
Temporomandibular joint (TMJ) arthritis on magnetic resonance imaging (MRI), but not ultrasound, is often found at the onset of juvenile idiopathic arthritis (JIA), according to Pennsylvania-based researchers.
Reuters Health Information, May 2008
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Golimumab Effective for Refractory Rheumatoid Arthritis
A long-acting monoclonal antibody to TNF-alpha, golimumab, is effective in treating patients with active rheumatoid arthritis despite treatment with methotrexate, according to a report in the April issue of Arthritis & Rheumatism.
Reuters Health Information, May 2008
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CME
FDA Safety Changes: Janumet, WelChol, Rituxan
The FDA has approved revisions to the safety labeling for sitagliptin plus metformin HCl tablets (Janumet), colesevelam HCl tablets (WelChol), and rituximab intravenous injection (Rituxan).
Medscape Medical News, May 2008
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Sulfasalazine for Rheumatoid Arthritis May Cause Severe Hepatotoxicity
Potentially fatal hepatotoxicity can be triggered by sulfasalazine therapy for rheumatoid arthritis, according to a series of case reports investigated by UK researchers.
Reuters Health Information, May 2008
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Height Loss Measurement Improves Sensitivity of Osteoporosis Diagnosis
Poor association between bone mineral density and vertebral fractures leads to misclassification of many osteoporotic patients.
Medscape Medical News, May 2008
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CME/CE
Guidelines Issued for Screening Men for Osteoporosis
The American College of Physicians recommend that clinicians assess risk factors for osteoporosis in older men and obtain a bone mineral density test for men at increased risk for osteoporosis.
Medscape Medical News, May 2008
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Abatacept Shows Ongoing Benefit in Arthritis Patients
The results of a 2-year follow-up study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate show the initial benefits of treatment are maintained and might even be enhanced.
Reuters Health Information, May 2008
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Recalls & Warnings Etanercept Gets Black Box Warning for TB Risk
Patients should be both screened for latent tuberculosis before initiation of etanercept therapy and monitored for infection during and after treatment.
Medscape Medical News, May 2008
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CME
Osteoporosis Drug Promotes Atrial Fibrillation in Population-Based Study
In a case-control study, women who have taken alendronate, the bisphosphonate widely prescribed for preservation of bone density, have an increased risk for the development of atrial fibrillation.
Medscape Medical News, April 2008
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Misdiagnoses Caused in Part by Overconfidence
The rate of diagnostic error is as high as 15%; physician overconfidence and a lack of feedback after diagnosis are the most important contributors to the problem.
WebMD Health News, April 2008
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Anti-TNF Drugs Equivalent for Treatment of Rheumatoid Arthritis
Tumor necrosis factor (TNF)-alpha blockers are equally effective for treatment of rheumatoid arthritis (RA), results of a meta-analysis indicate.
Reuters Health Information, April 2008
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CME
Urate Slows Progression of Parkinson's Disease
A study shows that urate, a naturally occurring metabolite and a major antioxidant in humans, may slow the progression of Parkinson's disease and thus could be an effective therapy for this disease.
Medscape Medical News, April 2008
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CME/CE
Review Addresses Strategies for Patient Adherence to Medications
An updated review provides various methods of encouraging patients to adhere to their medications, but the reviewers say that there are significant limitations and that more research is needed.
Medscape Medical News, April 2008
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Major Organ Involvement Common in Children With SLE
Most children who have systemic lupus erythematosus (SLE) have a variety of serious clinical manifestations, Canadian researchers report in the April issue of the Journal of Pediatrics.
Reuters Health Information, April 2008
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Non-Hodgkin Lymphoma Risk Increased by Some Autoimmune Disorders
The risk of developing non-Hodgkin lymphoma (NHL) is increased in certain, but not all, autoimmune disorders, according to a report in the April 15th issue of Blood.
Reuters Health Information, April 2008
