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Calcium Channel Gene Variant Increases Risk for Late-Onset Alzheimer's Disease
In a large case-control study, a CALHM1 variant was found to affect calcium permeability and amyloid precursor protein in the hippocampus.
Medscape Medical News, June 2008
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U.S. Electronic Health-Record Standards Agreed
U.S. consumer groups, insurers and privacy advocates together with Google Inc and Microsoft Corp said on Wednesday they have agreed to standards intended to speed adoption of personal electronic health records.
Reuters Health Information, June 2008
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Genetic Polymorphism Plus Other Factors Increase Congenital Heart Defect Risk
A nicotinamide N-methyltransferase (NNMT) polymorphism in association with periconception exposure to medicines and low dietary nicotinamide intake markedly increases the risk for congenital heart defects, according to a report in the June issue of the European Heart Journal.
Reuters Health Information, June 2008
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Combining Symptom Index With CA 125 Improves Detection of Ovarian Cancer
The addition of a simple symptom index to standard screening modalities improves the detection of both early- and late-stage ovarian cancer.
Medscape Medical News, June 2008
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CME
CVD Is a "Major Killer" in HIV+ Patients, but Underrecognized by Doctors
A unique meeting of cardiologists, endocrinologists, and HIV clinicians hopes to raise awareness of key facts about the risk for cardiovascular disease in people who are HIV positive.
Medscape Medical News, June 2008
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Prospective Results Suggest GCC Prognostic in Colorectal Cancer
A new study is encouraging experts to take another look at the potential of guanylyl cyclase C as a predictive marker.
Medscape Medical News, June 2008
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Personalized Medicine Requires Regulatory Change
Changes need to be made in the way therapies are developed, approved, and paid for if the potential of personalized medicine is to be realized, experts say.
Medscape Medical News, June 2008
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CME/CE
Treatment of Food Allergies Reviewed
In children and adults, the double-blind, placebo-controlled food challenge remains the most specific test to confirm the diagnosis of food allergies.
Medscape Medical News, June 2008
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Case Report of Advanced Melanoma Disappearing After T Cell Therapy
Advanced melanoma with lymph and lung metastases went into long-term complete remission after treatment with the patient's own cloned T cells.
Medscape Medical News, June 2008
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CME
Coffee Intake Not Linked to Increased Mortality in Men or Women
A study shows that coffee intake does not increase the risk for all-cause mortality in men or women and also shows a possible modest protective effect of coffee intake on cardiovascular mortality.
Medscape Medical News, June 2008
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Better Linkage After HIV Diagnosis Can Speed Initiation of Medical Care
Improving the linkage between HIV testing sites and treatment sites can speed the initiation of medical care after a diagnosis of HIV infection is confirmed, according to a report in the June 9th issue of the Archives of Internal Medicine.
Reuters Health Information, June 2008
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KINK-1 Increases Melanoma Sensitivity to Chemotherapy
KINK-1, a kinase inhibitor of nuclear factor kappa B (NFkB), increases the susceptibility of melanoma cells to antitumoral treatment, scientists from Germany report in the June 18th issue of the Journal of the National Cancer Institute.
Reuters Health Information, June 2008
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Topoisomerase-1 May Predict Chemotherapy Success in Colorectal Cancer
Levels of topoisomerase-1 (Topo1) appear to constitute a predictive biomarker for response to irinotecan in patients with advanced colorectal cancer, according to a study by a team of British researchers under Dr. Matthew T. Seymour.
Reuters Health Information, June 2008
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Promising New Agents and Treatment Failures in Melanoma
A review of new melanoma research presented at the ASCO meeting highlighted positive findings with axitinib, OncoVEX, and ipilimumab, but also highlighted the failure of tremelimumab and vaccination with ganglioside GM2-KLH21.
Medscape Medical News, June 2008
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CME
Management of GI Tract Complications Linked With Diabetes Reviewed
Gastrointestinal tract complications of diabetes include gastroparesis, intestinal enteropathy, and nonalcoholic fatty liver disease.
Medscape Medical News, June 2008
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CME
Estrogen May Be Neuroprotective After All
Positron emission tomographic scans show benefit in continuing estrogen long term in postmenopausal women at risk for Alzheimer's disease.
Medscape Medical News, June 2008
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CME
Glycemic Index and Load Linked to Risk for Colorectal and Endometrial Cancer
In a meta-analysis, glycemic index and glycemic load were directly linked with an increased risk for colorectal and endometrial cancer.
Medscape Medical News, June 2008
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CME
Women Who Smoke May Not Be at Higher Risk Than Men for Lung Cancer
In a large prospective study, men tended to have slightly higher incidence rates of lung cancer than women among ever-smokers with comparable smoking histories.
Medscape Medical News, June 2008
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New Small Molecule Inhibitors of Breast Cancer Cell Growth Identified
A team of U.S. scientists has identified a new family of compounds that block the ability of estrogen to stimulate the growth of breast cancer cells.
Reuters Health Information, June 2008
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New Test May Improve Detection of Latent TB in Rheumatoid Arthritis
A test that measures interferon-gamma release in response to bacterial antigens is more accurate than skin tests in detecting latent tuberculosis infection in patients with rheumatoid arthritis, new research shows. However, a second study found that this type of test yielded indeterminate results.
Reuters Health Information, June 2008
