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CME
Guidelines Discuss Use of Hydroxyurea in Treatment of Sickle Cell Disease
The National Institutes of Health have issued a conference consensus statement on the use of hydroxyurea in the treatment of sickle cell disease with an accompanying literature review.
Medscape Medical News, May 2008
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CME
Eosinopenia Reliably Identifies Sepsis in Critically Ill Patients
Eosinopenia is better than C-reactive protein at indicating sepsis in patients in intensive care units.
Reuters Health Information, May 2008
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Universal Rapid HIV Testing During Labor Feasible in Developing Countries
Rapid oral-fluid testing for HIV, counseling, and mother-to-child transmission (MTCT) prophylaxis in all women at the time of delivery are feasible and cost-effective in resource-poor settings, according to the results of a study from India.
Reuters Health Information, May 2008
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Cost -- Not Evidence -- Driving Shift in Cancer Screening
High-deductible health plans could be prompting patients to choose fully covered screening tests to avoid out-of-pocket expenses.
Medscape Medical News, May 2008
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CME
Inflammatory Markers Predict Congestive Heart Failure
The inflammatory markers IL-6, C-reactive protein, and macroalbuminuria suggest a mechanistic link between obesity and congestive heart failure, researchers say.
Medscape Medical News, May 2008
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Novel Cell-Based Therapy Shows Promise in Parkinson's Disease
Four-year results of a pilot study testing a novel cell-based therapy that appears to produce a continuous source of dopamine is showing promise in patients with moderate to advanced Parkinson's disease.
Medscape Medical News, May 2008
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CME
FDA Safety Changes: Janumet, WelChol, Rituxan
The FDA has approved revisions to the safety labeling for sitagliptin plus metformin HCl tablets (Janumet), colesevelam HCl tablets (WelChol), and rituximab intravenous injection (Rituxan).
Medscape Medical News, May 2008
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CME
Breast Cancer Within 2 Years of Childbirth Linked to Poor Prognosis
A study shows that women who have breast cancer within 2 years of their last pregnancy (or 2-4 years) after delivery are more likely to have a poor prognosis.
Medscape Medical News, May 2008
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Neuroblastoma Linked to Genetic Variants on Chromosome 6
Children with this genetic variant, identified for the first time in a genome-wide association study, develop a particularly aggressive form of neuroblastoma.
Medscape Medical News, May 2008
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Common Gene Variants Linked to Risk of Obesity and Insulin Resistance
Researchers have identified common variants near the gene for melanocortin-4 receptor (MC4R) that influence the risk of obesity and insulin resistance, according to findings from two studies appearing in the May 4th online issue of Nature Genetics.
Reuters Health Information, May 2008
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American Founder Mutation in Lynch Syndrome May Have Occurred 500 Years Ago
New research shows that a mutation responsible for hereditary nonpolyposis colon cancer (Lynch syndrome) originated centuries earlier and is more prevalent than previously believed.
Reuters Health Information, May 2008
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Urinary Biomarkers Show Promise in Diagnosing Brain Tumors
Urinary biomarkers are showing promise as an effective, noninvasive way of detecting the presence or recurrence of brain tumors, a new pilot study suggests.
Medscape Medical News, May 2008
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Research Finds Possible Link Between Allergies and Suicidality
Comorbidity data indicate a correlation that may be similar to the association with asthma and dermatitis.
Medscape Medical News, May 2008
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CME
Corticosteroids May Not Reduce Mortality in Children With Bacterial Meningitis
In a retrospective cohort study of children with bacterial meningitis, adjuvant treatment with corticosteroids was not associated with a decreased risk for death or shorter hospital stay.
Medscape Medical News, May 2008
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IL-1 Receptor Antagonist Preserves Beta-Cells in Type 1 Diabetes
The anti-inflammatory cytokine interleukin-1 receptor antagonist (IL-1ra) is associated with preserved beta-cell capacity in patients newly diagnosed with type 1 diabetes, according to European researchers.
Reuters Health Information, May 2008
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CME
Diagnosis and Management of Vulvar Skin Disorders Reviewed
The American College of Obstetricians and Gynecologists has issued a practice bulletin reviewing available diagnostic methods and management strategies for vulvar skin disorders.
Medscape Medical News, May 2008
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CME
Routine Vaccination With Quadrivalent Meningococcal Conjugate Vaccine Not Recommended for Certain Children
The Advisory Committee on Immunization Practices does not recommend routine vaccination of children ages 2 to 10 years with quadrivalent meningococcal conjugate vaccine.
Medscape Medical News, May 2008
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Aberrant Karyotypes More Common in Infertile Couples
Infertile couples appear more likely to have aberrant karyotypes compared with the general population, according to Italian researchers.
Reuters Health Information, May 2008
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Intrahepatic Vein Safer and More Successful for Fetal Blood Sampling
The success rate is higher and bleeding from the sampling site much lower with fetal blood collected via the intrahepatic vein compared with cordocentesis, a team from Johns Hopkins University School of Medicine reports in the April issue of the American Journal of Obstetrics and Gynecology.
Reuters Health Information, May 2008
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Single Gene Variant Linked to Severe Diabetes Complications
A functional polymorphism in the erythropoietin promoter may be associated with more severe microvascular complications of the eye and kidney in patients with diabetes, according to a report in the May 13th issue of the Proceedings of the National Academy of Sciences.
Reuters Health Information, May 2008
