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New Risk Factors for Cardiovascular Problems After Joint Surgery Identified
In addition to confirming previously identified risk factors for cardiovascular complications after total joint replacement (TJR) surgery, researchers have shown that bilateral and revision operations are associated with increased risk.
Reuters Health Information, August 2008
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Apolipoprotein E Genotype May Affect Cognitive Decline in Those Nearing 70
The *E4 allele of apolipoprotein E (APOE) may be associated with poorer cognitive performance among people aged 65-69, and may interact with risk factors such as head trauma to influence the rate of cognitive decline, according to an Australian study published online on July 14 by BioMed Central Geriatrics.
Reuters Health Information, August 2008
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Changes in Folate and Homocysteine Linked to Incident Dementia
Onset of dementia is associated with decreasing folate and increasing vitamin B12 and homocysteine, results of a study published in the August issue of the Journal of Neurology, Neurosurgery, and Psychiatry indicate.
Reuters Health Information, August 2008
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Outcome Variable With Hemorrhagic Transformation of Ischemic Stroke
The prognosis with early hemorrhagic transformation, a complication in about 9% of ischemic strokes, varies according to type, Italian researchers say.
Reuters Health Information, August 2008
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Positive Parenting May Prevent Social Aggression in Early-Maturing Girls
Girls who start their periods a year earlier than their peers and who do not have parents with positive parenting skills are more likely to be socially aggressive, new research shows.
Medscape Medical News, August 2008
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Tibolone Decreases Fracture, Breast Cancer, but Doubles Stroke Risk
Results of the randomized LIFT trial show that tibolone, approved for treatment of menopausal symptoms, has positive effects on fracture, breast cancer, and possibly colon cancer but increased stroke risk in women with osteoporosis and should not be used in those with stroke risk factors.
Medscape Medical News, August 2008
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Recalls & Warnings FDA and Boston Scientific Recall NexStent Carotid Stent System
The FDA and Boston Scientific announced a class 1 recall of the NexStent Monorail, NexStent carotid stent, and Monorail delivery system, distributed between June 2007 and May 2008, because the tip of the stent-delivery system may detach.
Medscape Medical News, August 2008
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Framingham: Alcohol Consumption Declines, Dependence Risk Remains
New results from the Framingham Heart Study show that over the past 50 years, average alcohol consumption has declined. However, the risk of developing alcohol dependence and associated alcohol-related conditions has not decreased.
Medscape Medical News, August 2008
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Retinopathy Ups CHD Risk Even Without Diabetes
A new study has found that retinopathy is associated with an increased risk of coronary heart disease, regardless of whether or not the person has diabetes.
Heartwire, August 2008
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Gabapentin May Help Alcoholics Recover From Dependence
A pilot study suggests that small doses of gabapentin taken at night may deter heavy drinking.
Medscape Medical News, August 2008
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On-TIME 2 in Print: Acute STEMI Gains with Prehospital Triple Antiplatelet Therapy
Adding tirofiban to therapy with clopidogrel, aspirin, and heparin while the patient is in transit to a PCI center improves ST-segment resolution; outcomes may also improve, the trial hinted.
Heartwire, August 2008
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CME
Excessive Alcohol Intake May Increase Risk for Active Tuberculosis
A systematic review shows that people who drink more than 40 g of alcohol per day and/or have an alcohol disorder are at greater risk for active tuberculosis.
Medscape Medical News, August 2008
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CME
Vitamin K Supplementation May Reduce Progression of Insulin Resistance in Older Men
A study shows that vitamin K supplementation for 36 months at doses attainable in the diet may reduce progression of insulin resistance in older men.
Medscape Medical News, August 2008
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CME
Salmeterol Plus Fluticasone Slows Disease Progression in Moderate to Severe COPD
A post hoc analysis of a large randomized controlled trial shows that a combination of salmeterol plus fluticasone significantly slows the progression of chronic obstructive pulmonary disease.
Medscape Medical News, August 2008
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CME
Overall Healthy Lifestyle Significantly Reduces Stroke Risk
A new analysis confirms that in addition to preventing chronic diseases such as diabetes and heart disease, an overall healthy lifestyle is associated with a significantly decreased stroke risk.
Medscape Medical News, August 2008
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Birth Control Pill Alters Women's Perception of Male Body Odor
If body odor plays a role in women's choice of a mate, then oral contraception use may affect the selection process, according to researchers in the UK. They have shown that genotype-correlated odor preferences are shifted in women taking the pill, leading to selection of genetically similar rather than dissimilar men.
Reuters Health Information, August 2008
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Fibrotic Damage by HIV Limits Immune Reconstitution in Lymphatic Tissues in Gut
Early in the course of HIV infection, collagen deposition in gut-associated lymphatic tissues (GALT) causes greater CD4+ T cell depletion than in other lymph tissues and limits the extent of immune reconstitution that can be achieved with antiretroviral medications, according to research by scientists at the University of Minnesota in Minneapolis and at the National Institutes of Health in Bethesda, Maryland.
Reuters Health Information, August 2008
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Two-Tier Serologic Testing Provides Good Specificity for Diagnosing Lyme Disease
The 2-tier serologic test for Lyme disease provides better specificity than the C6 peptide ELISA method, according to a report in the July 15th issue of Clinical Infectious Diseases.
Reuters Health Information, August 2008
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FDA Issues Draft Report on Bisphenol A: "Adequate Margin of Safety" in Typical Exposure
The FDA has issued a draft report on bisphenol A, noting "adequate margin of safety" in typical exposure from food.
WebMD Health News, August 2008
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FDA Approves First Drug for Treatment of Chorea in Huntington's
The FDA has announced approval for tetrabenazine, the first drug approved for any symptom of Huntington's disease.
Medscape Medical News, August 2008