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Rethinking Daily Exercise: Less Regular, High-Intensity Intervals May Be Best Bet for Metabolic Syndrome
The study found that subjects who added short intervals of high-intensity exercise to a three-times-per-week regimen experienced greater improvements in endothelial function, blood pressure lowering, insulin sensitivity, fasting glucose, and HDL cholesterol. Investigators say it is time to seriously rethink the idea that moderate physical activity for 30 minutes daily is the best way to reduce CV risk.
Heartwire, July 2008
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Men With Breast Cancer are Diagnosed at Later Stage Than Women
Twice as many men as women have locally advanced disease on diagnosis, suggesting that there are delays in taking action by both patients and physicians.
Medscape Medical News, July 2008
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Circulating Tumor Cells Predict Overall Survival in Prostate Cancer
Fewer circulating tumor cells were significantly correlated with longer survival in patients with castration-resistant prostate cancer.
Medscape Medical News, July 2008
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Vaccine Shows No Benefit in Renal Cell Carcinoma
The heat-shock protein peptide complex, which was showing promise in early study, has failed a phase 3 trial.
Medscape Medical News, July 2008
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CHD5 Gene Suppression Tied to Poor Outcome in Neuroblastomas
Low CHD5 expression is associated with poorer outcome in patients with neuroblastomas, researchers report in the July 2nd issue of the Journal of the National Cancer Institute
Reuters Health Information, July 2008
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No Lasting Neuropsychological Effects of Chemotherapy for ALL in Children
Two years after the end of potentially neurotoxic intrathecal and systemic chemotherapy, no major differences in neuropsychological outcome were found between pediatric patients with acute lymphoblastic leukemia (ALL) and their healthy siblings.
Reuters Health Information, July 2008
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Smoking, Alcohol Among Risk Factors for Vulvar/vaginal Carcinoma
Risk factors for invasive squamous cell carcinoma of the vulva and vagina include human papillomavirus (HPV) infection, tobacco smoking, and alcohol consumption, according to a Danish study published June 15th in the International Journal of Cancer.
Reuters Health Information, July 2008
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Controversial End-of-Life Care Bill Amended in California
The bill is designed to improve information and counseling for patients, but it also encourages the use of palliative sedation and voluntary starvation and dehydration, and has been met with strong opposition.
Medscape Medical News, July 2008
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Motesanib Effective in Progressive Differentiated Thyroid Disease
The experimental drug motesanib might be "clinically useful" in progressive differentiated thyroid disease, say researchers reporting a phase 2 trial.
Medscape Medical News, July 2008
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IL-7 Therapy Boosts Immune Response in Cancer Patients
Treatment with recombinant human interleukin-7 was shown to safely induce polyclonal T cell expansion, resulting in dramatic increases in T cell numbers, in patients with refractory cancer
Medscape Medical News, July 2008
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Practical Intervention Addresses Depression in Cancer Patients
Nurses with no previous psychiatric experience can deliver a cost-effective collaborative intervention for cancer patients, researchers show.
Medscape Medical News, July 2008
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Pegylated Liposomal Doxorubicin Effective in Hard-To-Treat Cutaneous T-Cell Lymphoma
Pegylated liposomal doxorubicin (Caelyx; Schering-Plough) is an effective therapy for advanced or refractory cutaneous T-cell lymphoma (CTCL), results of a study confirm.
Reuters Health Information, July 2008
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Survival After Radical Cystectomy Linked to Number of Lymph Nodes Removed
More extensive lymphadenectomy is associated with improved survival in patients with lymph node-positive bladder cancer undergoing radical cystectomy, according to a report in the June 1st Cancer.
Reuters Health Information, July 2008
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Novel Cancer Therapy Moving to Human Trials
After experiencing dramatic results with cancer-resistant mice, an investigational new cancer treatment that transfers the naturally occurring cancer-killing activity of granulocytes from a selected donor to a cancer patient is about to begin a phase 2 trial.
Medscape Medical News, July 2008
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CME
Chronic Diseases Linked to Invasive Pneumococcal Disease in Children
In a case-control study, cancer, chronic renal diseases, splenectomy, and transplantation were strongly associated with an increased risk for invasive pneumococcal disease in children.
Medscape Medical News, July 2008
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CME
FDA Approvals: PrandiMet, Doryx, Doxil
The FDA has approved repaglinide plus metformin HCl tablets (PrandiMet), doxycycline hyclate 150-mg tablets (Doryx), and a new indication for doxorubicin liposome injection (Doxil).
Medscape Medical News, July 2008
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Anti-Thrombosis Benefit Unclear in Cancer Patients With Catheters
Pooled data from randomized trials does not clearly demonstrate a significant advantage for thromboprophylaxis in cancer patients with central venous catheters, according to North American and Italian researchers.
Reuters Health Information, July 2008
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Maribavir Prevents CMV Infection After Stem Cell Transplant
Maribavir, a novel inhibitor of a viral protein kinase of human cytomegalovirus (CMV), reduces the incidence of CMV infection in allogeneic stem cell transplant recipients, according to a report in the June 1st issue of Blood.
Reuters Health Information, July 2008
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KRAS Mutations Predictive But Not Prognostic in Colorectal Cancer
Another study has confirmed that KRAS mutations predict response to cetuximab in colorectal cancer, but shows that they are not prognostic.
Medscape Medical News, July 2008
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Smoke-Free Policies Bring Health Benefits
The International Agency for Research on Cancer has announced that the implementation of smoke-free policies in many Western countries has reduced the prevalence of smoking and had subsequent health benefits.
Heartwire, July 2008
