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Excess Interleukin-21 Found in Intestinal Mucosa of Celiac Disease Patients
The cytokine interleukin 21 (IL-21) is overproduced in the intestinal mucosa of patients with untreated celiac disease (CD), where it helps to sustain the production of interferon-gamma (IFN-gamma), according to a study by Italian and British researchers published in the July issue of Gut.
Reuters Health Information, June 2008
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U.S. Electronic Health-Record Standards Agreed
U.S. consumer groups, insurers and privacy advocates together with Google Inc and Microsoft Corp said on Wednesday they have agreed to standards intended to speed adoption of personal electronic health records.
Reuters Health Information, June 2008
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Insulin Resistance, Diabetes Increase Liver Fibrosis in Patients With Genotype 1 HCV
Insulin resistance is a major determinant of advanced hepatic fibrosis in patients with chronic hepatitis C resulting from genotype 1 (G1-HCV), especially in the presence of severe necroinflammation, according to study findings published in the May issue of the American Journal of Gastroenterology.
Reuters Health Information, June 2008
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Outcomes Similar With Resective or Drainage Procedures in Pancreatitis
Long-term follow-up of chronic pancreatitis patients who underwent the pylorus-preserving variant of the Whipple resection procedure shows that results are ultimately comparable to those achieved using the more recent Frey organ-sparing extended drainage approach, according to German researchers.
Reuters Health Information, June 2008
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Probiotic Relieves Diarrhea in Infants and Toddlers
The probiotic Escherichia coli Nissle 1917 is effective in treating diarrhea greater than 4 days' duration in infants and toddlers, according to a report in the June issue of The Pediatric Infectious Disease Journal.
Reuters Health Information, June 2008
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CME
Corticosteroids Linked to Increased Mortality Rate in Inflammatory Bowel Disease
A retrospective cohort study shows that patients with inflammatory bowel disease treated with corticosteroids, but not thiopurines, are at increased risk for death.
Medscape Medical News, June 2008
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Prospective Results Suggest GCC Prognostic in Colorectal Cancer
A new study is encouraging experts to take another look at the potential of guanylyl cyclase C as a predictive marker.
Medscape Medical News, June 2008
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Survey Assesses Bariatric Surgeons' Expectations and Risk Tolerance for Endoluminal Procedures
Acceptable risk and weight-loss expectations differ for primary and revisional procedures.
Medscape Medical News, June 2008
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Personalized Medicine Requires Regulatory Change
Changes need to be made in the way therapies are developed, approved, and paid for if the potential of personalized medicine is to be realized, experts say.
Medscape Medical News, June 2008
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CME/CE
Treatment of Food Allergies Reviewed
In children and adults, the double-blind, placebo-controlled food challenge remains the most specific test to confirm the diagnosis of food allergies.
Medscape Medical News, June 2008
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Terlipressin May Improve Hepatorenal Syndrome, but Ischemic Risks Seen
Combination treatment with albumin and the vasopressin analogue terlipressin can improve renal function in patients with hepatorenal syndrome and advanced liver disease, according to new research.
Reuters Health Information, June 2008
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New Bariatric Technique Using Gastric Tube Retains Duodenal Function, Avoids Dumping
Sleeve gastrectomy with enteral bypass has advantages over sleeve gastrectomy alone.
Medscape Medical News, June 2008
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Hold the Tomatoes: CDC and FDA Update Clinicians on the Salmonella Outbreak
The agencies advise clinicians to watch for certain symptoms as the number of infected nears 600 people in 30 states.
Medscape Medical News, June 2008
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Irbesartan Added to Propranolol May Improve Cirrhosis Therapy
Combination therapy with irbesartan and propranolol can produce greater sodium excretion than use of propranolol alone in certain patients with cirrhosis, according to German researchers.
Reuters Health Information, June 2008
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Rate and Degree of Weight Loss After Gastric Bypass Governs Diabetes Outcome
The amount of weight lost within the first few months after gastric bypass surgery is a key determinant of whether severe type 2 diabetes will go into remission, according to surgeons at Duke University Medical Center in Durham, North Carolina.
Reuters Health Information, June 2008
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Gastric Band Failure Data Important for Comparisons With Gastric Bypass
Both excluding and including treatment failure data from clinical follow-up trials can introduce bias.
Medscape Medical News, June 2008
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CME
French Study Identifies Factors That Predict Success in Gastric Banding Procedure
Multidisciplinary approach and experienced surgical team were linked to successful decrease in excess body weight after gastric banding.
Medscape Medical News, June 2008
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CME
Single-Dose MMX Mesalazine May Be Effective for Ulcerative Colitis
A study shows that 2.4 g/day of mesalazine with Multi Matrix Technology in a single dose is as effective as the twice-daily dose in achieving maintenance of remission for ulcerative colitis.
Medscape Medical News, June 2008
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Studies Show Quality of Life Linked to Cancer Survival
Patients reporting a good quality of life have statistically significant better overall survival, suggest 2 large meta-analyses.
Medscape Medical News, June 2008
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Longer Treatment Course Advisable With Hepatitis C Genotype 6
There is a higher rate of sustained virologic response in patients with chronic hepatitis C virus (HCV) genotype 6 infection who are treated for 48 weeks with peginterferon or interferon and ribavirin, compared to those who receive only 24 weeks of treatment, according to California-based investigators.
Reuters Health Information, June 2008
