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Athletic Benefit of Growth Hormone May Be Psychological
The placebo effect may contribute to the perceived and actual performance-enhancing effects of growth hormone in athletes, particularly in men, according to research presented today at the Endocrine Society's 90th annual meeting in San Francisco.
Reuters Health Information, June 2008
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Amgen's Enbrel in Kids 'Concerning,' FDA Staff Says
U.S. drug regulators are concerned about life-threatening complications in children taking Amgen Inc's drug Enbrel for psoriasis and other conditions, according to documents released on Monday.
Reuters Health Information, June 2008
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Amniotic Membranes Rapidly Reverse Skin Detachment Caused by Epidermal Necrolysis
In a case report of a woman with lamotrigine-induced toxic epidermal necrolysis (TEN), placement of amniotic membranes over areas of epidermal detachment led to complete re-epithelialization within 5 days.
Reuters Health Information, June 2008
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Cosmetic Surgery Booming in Britain, Study Finds
Britons might be feeling the pinch of the global credit crunch, but they're still ready to pay thousands of pounds for cosmetic surgery, a report suggested on Monday.
Reuters Health Information, June 2008
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Telavancin Effective for Treating Complicated Skin Infections
Telavancin is at least as effective as vancomycin for treating complicated skin and skin-structure infections (SSSI), according to a report in the June 1st Clinical Infectious Diseases.
Reuters Health Information, June 2008
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US FDA Staff Sees Risks With Investigational Psoriasis Drug
An experimental psoriasis drug from Johnson & Johnson was effective in clinical trials, but long-term use may increase the risk of cancer, U.S. drug reviewers said in documents released on Friday.
Reuters Health Information, June 2008
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CME
Methotrexate Treatment of Rheumatoid Arthritis Increases Risk for Certain Cancers
A study shows that patients with rheumatoid arthritis treated with methotrexate are at an increased risk for melanoma, non-Hodgkin's lymphoma, and lung cancer.
Medscape Medical News, June 2008
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Recalls & Warnings Diabetic Ulcer Gel Gets Black Box Warning
An FDA safety review showed a 5-fold increased risk for cancer mortality in patients exposed to 3 or more tubes of becaplermin gel.
Medscape Medical News, June 2008
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Valacyclovir Effective for Herpes Zoster in Immunocompromised Adults
Valacyclovir, the oral prodrug of acyclovir, is effective for treating uncomplicated herpes zoster in immunocompromised adults, according to a report in the May 1st issue of The Journal of Infectious Diseases.
Reuters Health Information, June 2008
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Targeting N-Cadherin Boosts Melanoma Response to Chemotherapy
A novel pentapeptide -- ADH-1 -- that disrupts N-cadherin-mediated cell adhesion, enhances the response of melanoma to cytotoxic chemotherapy, according to the results of an animal study published in the May 15th issue of Cancer Research.
Reuters Health Information, May 2008
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Acne Treatment Linked to Depression
Use of isotretinoin for acne vulgaris apparently more than doubles the risk of depression, according to the results of a case-crossover study. Still, the absolute risk is probably very small.
Reuters Health Information, May 2008
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Breast Intensity-Modulated Radiotherapy Curbs Acute Skin Reactions
Breast intensity-modulated radiation therapy (IMRT) reduces the incidence of acute radiation dermatitis, compared to standard radiotherapy using wedges, results of a multicenter randomized study indicate.
Reuters Health Information, May 2008
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Sorafenib Plus Dacarbazine Shows Promise in Advanced Melanoma
In a phase II study of chemotherapy-naive patients with stage III (unresectable) or stage IV melanoma, the addition of the Raf kinase inhibitor sorafenib to dacarbazine yielded an "encouraging" improvement in progression-free survival, the primary endpoint, and was well tolerated, researchers report.
Reuters Health Information, May 2008
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What Your Patients Are Reading: Erectile Dysfunction in Diabetics Predictive of Coronary Artery Disease
Erectile dysfunction in men with type 2 diabetes is an independent predictor of cardiac adverse events, asthma may increase the risk for
suicidal ideation with suicide attempts in some patients, aprotinin's link to excess deaths was affirmed in final results of the BART study,
adding ultrasound to mammography increases cancer detection but also raises false-positive rates, and shingles risk is associated with a
family history of herpes zoster.
Medscape Medical News, May 2008
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CME
FDA Approvals: Taclonex Scalp, Abilify, Levaquin
The FDA has approved calcipotriene hydrate plus betamethasone dipropionate, an expanded indication for aripiprazole, and an expanded indication for levofloxacin.
Medscape Medical News, May 2008
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Polyalkylimide Dermal Fillers Linked to Inflammatory and Granulomatous Reactions
A study has shown that polyalkylimide implants can infrequently result in delayed and recurrent chronic inflammatory and granulomatous reactions.
Medscape Medical News, May 2008
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CME
Shingles Linked to Family History of Herpes Zoster
A case-control study showed that there is an association between shingles and a family history of herpes zoster.
Medscape Medical News, May 2008
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CME/CE
Guidelines Issued on Prevention of Herpes Zoster
The Advisory Committee on Immunization Practices has issued guidelines on the prevention of herpes zoster.
Medscape Medical News, May 2008
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U.S. Regulator Agrees to Study Botox Rival
French drugs group Ipsen and its U.S. partner Medicis said on Monday the Food and Drug Administration had agreed to evaluate Reloxin for cosmetic use in a potential boost for the would-be Botox competitor.
Reuters Health Information, May 2008
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Interleukin 12/23 Monoclonal Antibody Useful for Psoriasis
Ustekinumab, a human monoclonal antibody directed against interleukin 12 and 23, is an effective treatment for moderate-to-severe psoriasis, according to the results of the PHOENIX 1 and 2 trials appearing in the May 17th issue of The Lancet.
Reuters Health Information, May 2008
