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Zoledronic Acid Significantly Reduced Relapse in Early Breast Cancer
For the first time, a bisphosphonate has shown a substantial clinical benefit in early breast cancer, reducing both local and distant disease.
Medscape Medical News, June 2008
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Oral Capecitabine Inferior to Conventional Chemo in Elderly Breast Cancer Patients
In older women with early-stage breast cancer, single-agent oral capecitabine was inferior to 2 different conventional chemotherapy regimens.
Medscape Medical News, June 2008
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Breast Intensity-Modulated Radiotherapy Curbs Acute Skin Reactions
Breast intensity-modulated radiation therapy (IMRT) reduces the incidence of acute radiation dermatitis, compared to standard radiotherapy using wedges, results of a multicenter randomized study indicate.
Reuters Health Information, May 2008
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Short-Interval Follow-Up Mammograms for "Probably Benign" Lesions Have Low Sensitivity
Diagnostic short-interval mammograms obtained to follow patients with "probably benign" lesions have a low sensitivity for detecting cancers diagnosed within the following 12 months, according to a paper in the May issue of the American Journal of Roentgenology.
Reuters Health Information, May 2008
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Microenvironment May Predict Invasive Spread of Ductal Carcinoma in Situ
The transition of ductal carcinoma in situ (DCIS) into invasive breast carcinoma may be caused by changes in the myoepithelial cells that line the milk ducts, according to a report in the May issue of Cancer Cell.
Reuters Health Information, May 2008
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Vitamin D Deficiency Linked to Poorer Outcome in Breast Cancer
Women deficient in vitamin D when diagnosed with breast cancer had significantly worse outcomes than those with normal levels.
Medscape Medical News, May 2008
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Mastectomy Rates Have Risen Recently, as Has Breast MRI
Mayo Clinic researchers reporting a rise in mastectomy rates at the same time as an increase in preoperative breast MRI speculate that the two are related.
Medscape Medical News, May 2008
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New Findings to Be Presented at ASCO 2008 Meeting
For the first time, the American Society of Clinical Oncology has released several key research findings ahead of its annual meeting, being held later this month.
Medscape Medical News, May 2008
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Ultrasound Added to Mammography Finds More Breast Cancer
For women at high risk for breast cancer, adding ultrasound screening to mammography finds more cases of cancer, but increases the false-positive rate.
Medscape Medical News, May 2008
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Exercise Protects Against Premenopausal Breast Cancer
Exercise has been consistently associated with a decrease is the risk for postmenopausal breast cancer, but a new study shows that it also protects against premenopausal breast cancer.
Medscape Medical News, May 2008
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Lapatinib Not Cost Effective, Editorialists Argue
Ringing in at roughly US$2900 a month, experts are questioning whether a new treatment schedule or other strategies can be used to make the drug more accessible.
Medscape Medical News, May 2008
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Taxanes Confer Limited Benefit in Metastatic Breast Cancer
A meta-analysis of studies of taxanes alone or in combination with anthracyclines as first-line therapy for patients with metastatic breast cancer shows that neither approach provides a survival advantage.
Reuters Health Information, May 2008
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Cost -- Not Evidence -- Driving Shift in Cancer Screening
High-deductible health plans could be prompting patients to choose fully covered screening tests to avoid out-of-pocket expenses.
Medscape Medical News, May 2008
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Medicare Expected to Exceed $21 Billion for Elderly Cancer Patients
The startling estimate is based on 5 years of cancer care for American patients 65 years or older.
Medscape Medical News, May 2008
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Breast Cancer and Implants: Surgery Options
Breast-conserving surgery may be an option for women with breast implants and breast cancer.
WebMD Health News, May 2008
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Variants in Vitamin D Receptor Gene Tied to Breast Cancer Risk
Certain vitamin D receptor (VDR) gene polymorphisms could affect the risk of breast cancer, as well as the estrogen receptor status of tumors, in postmenopausal women, according to findings from a German study.
Reuters Health Information, April 2008
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Exemestane May Improve Survival After Tamoxifen Therapy
In women with early-stage, hormone receptor-positive breast cancer, extended therapy with the steroidal aromatase inhibitor exemestane after 5 years of treatment with tamoxifen significantly improves relapse-free survival, according to an analysis of the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-33 trial.
Reuters Health Information, April 2008
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Tamoxifen More Effective in Breast Cancer Patients With Certain Genotype
In women with a certain genotype, tamoxifen is as effective as — or more effective than — aromatase inhibitors in reducing the risk for breast cancer relapse.
Medscape Medical News, April 2008
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Researchers Point to Flaws in Recent Cancer Studies
Observational studies of treatment outcomes must be viewed with caution, investigators urge.
Medscape Medical News, April 2008
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Two Variants Increase Risk for Hormone-Positive Breast Cancer
A study of more than 6000 cases suggests that genes are specific to estrogen-receptor status of breast tumors.
Medscape Medical News, April 2008
