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Capecitabine Plus Oxaliplatin (CapOx) Versus Capecitabine Plus Gemcitabine (CapGem) Versus Gemcitabine Plus Oxaliplatin (mGemOx): A Multicenter Randomized Phase II Trial in Advanced Pancreatic Cancer
Capecitabine plus oxaliplatin, capecitabine plus gemcitabine, and gemcitabine plus oxaliplatin may all provide the same clinical benefit in advanced pancreatic cancer with manageable side effects.
Journal Article, May 14, 2008
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CME/CE
NCCN Breast Cancer Guidelines Update
Review the most current NCCN guidelines on management strategies for breast cancer.
Slide/Lecture Presentation, May 14, 2008
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Antidepressants and Risk of Prostate Cancer: A Nested Case-Control Study
This study examined the association between antidepressant drug use and risk of prostate cancer.
Journal Article, May 13, 2008
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Why the NIH Trial to Assess Chelation Therapy (TACT) Should Be Abandoned
The $30 million, NIH Phase 3 Trial to Assess Chelation Therapy (TACT) exposes subjects to a risky method that is known to be ineffective. The TACT should be abandoned and its origins investigated.
Article, May 13, 2008
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CME
Importance of Surgical Margins in the Management of Renal Cell Carcinoma
Partial nephrectomy is more commonly used for renal cell carcinoma, but there are concerns about complete tumor excision with this procedure. The current review examines the data in regard to this issue as well as best practices to improve the success of partial nephrectomy.
Journal Article, May 13, 2008
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The Breast Cancer Continuum in Hormone-Receptor-Positive Breast Cancer in Postmenopausal Women: Evolving Management Options Focusing on Aromatase Inhibitors
Third generation aromatase inhibitors have shown superior efficacy to tamoxifen in the metastatic, neoadjuvant, and adjuvant settings.
Journal Article, May 9, 2008
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Icyou: How Social Media Is the New Resource for Online Health Information
Prerna Mona Khanna, MD, MPH, Medical Editor, Icyou.com, Charleston, South Carolina, describes another promising use of the health Internet.
Expert Viewpoint, May 9, 2008
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Congress Passes Genetic Privacy Bill
In this videoblog, Dr. Eric Topol updates us on some of the details and discusses what this might mean for the future if it is signed into law.
Expert Viewpoint, May 8, 2008
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The Equivocally Amplified HER2 FISH Result on Breast Core Biopsy: Indications for Further Sampling Do Affect Patient Management
Might an equivocal HER2 amplification result from a breast core biopsy specimen be consistently representative of the HER2 status of the overall breast tumor? What are the testing implications?
Journal Article, May 8, 2008
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Can A Topical Immunomodulating Agent Obviate Need for Surgery in Vulvar Intraepithelial Neoplasia?
Results of a small placebo-controlled study suggest that a topical cream may serve as an alternative to surgery for some patients with vulvar intraepithelial neoplasia.
Expert Viewpoint, May 7, 2008
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Do Women Comply with Recommendations for Papanicolaou Smears Following Colposcopy? A Retrospective Study
Do women with abnormal Pap smears comply with follow-up cervical cancer screening or care after completing colposcopic exams and treatment? Patient compliance is evaluated in this study.
Journal Article, May 7, 2008
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Consensus Guidelines for the Management of Radiation Dermatitis and Coexisting Acne-like Rash in Patients Receiving Radiotherapy Plus EGFR Inhibitors for the Treatment of Squamous Cell Carcinoma
This paper reviews the consensus guidelines for the treatment of radiation dermatitis in patients with squamous cell carcinoma of the head and neck receiving EGFR inhibitors plus radiotherapy.
Journal Article, May 7, 2008
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Update on Vaccines for Melanoma Patients
Vaccination against melanoma has a long history but only recently has this therapeutic approach found a reliable scientific rationale.
Journal Article, May 7, 2008
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Pharmacovigilance in Nephrology
Recent controversies about heparin contamination from China and ESA adverse effects raise questions about drug safety and FDA oversight.
Expert Viewpoint, May 6, 2008
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CME/CE
NCCN Task Force Report: Prevention and Management of Mucositis in Cancer Care
Review how these updated NCCN findings will impact the management of mucositis secondary to cancer therapy.
Slide/Lecture Presentation, May 6, 2008
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Analysis of Chromosome 1p Abnormalities in Renal Oncocytomas by Loss of Heterozygosity Studies: Correlation With Conventional Cytogenetics and Fluorescence In Situ Hybridization
In renal oncocytomas, how often do chromosome 1 abnormalities occur using loss of heterozygosity studies? How do 3 techniques compare in the evaluation of chromosome 1 in renal oncocytomas?
Journal Article, May 5, 2008
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How to Treat Skin Infections, Including MRSA, in 2008
Erik Schraga, MD, with Stanford-Kaiser Santa Clara Emergency Medicine in California, explains the correct way to treat skin abscesses in 2008.
Editorial, May 5, 2008
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CME
Management of Surgical Patients with VWD: New Research-based Options
Review how to properly treat and monitor patients with VWD preoperatively and postoperatively, and explore therapeutic approaches for VWD during various surgical procedures.
Slide/Lecture Presentation, May 5, 2008
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Association of Human Papillomavirus With Vulvar and Vaginal Intraepithelial Disease: Opportunities for Prevention
What is the prevalence of human papillomavirus (HPV) infection in vaginal and vulvar neoplasias and cancers? What proportion of these diseases might be prevented by the quadrivalent HPV vaccine?
Journal Article, May 2, 2008
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Patients: An Untapped Safety Resource
Julia A. Hallisy, DDS, a dentist in San Francisco, California, teaches how patients can protect themselves.
Editorial, May 2, 2008
